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| ID | Type | Description | Link |
|---|---|---|---|
| UH2AG050311 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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This is a large pragmatic, randomized controlled trial to test the real-world effectiveness of inpatient palliative care consultative services in improving a number of patient- and family-centered processes and outcomes of care among seriously ill hospitalized patients. The investigators hypothesize that improved patient-centered outcomes can be achieved without higher costs by simply changing the default option for inpatient palliative care consultation for eligible patients from an opt-in to an opt-out system. To test this hypothesis the investigators will conduct a clinical trial at 11 hospitals using the same electronic health record within Ascension Health, the largest non-profit health system in the U.S.
The REDAPS trial aims to generate large-scale, experimental evidence regarding the real-world effectiveness of inpatient palliative consultative services (IPCS) and to test the incremental effectiveness and costs of a simple, scalable method to increase IPCS utilization among properly selected patients. The REDAPS trial will also compare the effectiveness of different palliative care team structures and services and identify patient subgroups most likely to benefit from IPCS. To achieve these goals, the investigators will conduct a clinical trial at 11 Ascension Health hospitals using the same electronic health record. Participating hospitals first contribute a minimum of 4 months of data under the control paradigm (opt-in model), where physicians must identify patients who may benefit from palliative care consultation and actively order such services. Then, using a stepped-wedge design, the hospitals are randomly assigned to begin the intervention in intervals spaced approximately 2.7 months apart. During the intervention, patients meeting consensus criteria for eligibility for palliative care consultation are identified by the electronic health record, a consultation is ordered by default, physicians may cancel the order after being alerted to it, and patients or family members may decline such services. By the end of the trial, all hospitals will have utilized the intervention paradigm of palliative care consultation for at least 4 months. The REDAPS trial will compare outcomes (clinical, economic, and process measures) before and after implementation within hospitals, as well as comparisons among hospitals at given time points.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Default ordering of palliative consult | Active Comparator | Hospitals randomized to the intervention arm will adopt a system whereby eligible patients are identified by the electronic health record, a consultation is ordered by default, and physicians may cancel the order after being alerted to it, and patients or family members may decline such services. |
|
| Usual care | No Intervention | There will be no trial-driven approach to care. Inpatient palliative care consultative services will be actively requested by physicians as in usual care. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Default ordering of palliative consult | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| Composite Measure: Length of Stay and In-Hospital Mortality | The primary outcome is a composite measure of in-hospital mortality and hospital length-of-stay that ranks deaths along the length-of-stay distribution. Data is extracted from the electronic health record. | Duration of hospital stay, an expected average of 8 days |
| Measure | Description | Time Frame |
|---|---|---|
| Goals of care assessment | Documented assessments of patients' goals of care within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Pain assessment | Documented assessments of patients' pain scores within the electronic health record |
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Inclusion Criteria:
Age 65 years or older
Current hospitalization of at least 3 calendar days (modified ITT)
Diagnosis of one or more of the following:
Exclusion criteria:
1. Patients younger than 65 years old will not receive the intervention
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| Name | Affiliation | Role |
|---|---|---|
| Scott D Halpern, PhD,MD | University of Pennsylvania | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St. Vincent's Medical Center | Bridgeport | Connecticut | 06606 | United States | ||
| St. Vincent's Medical Center, Riverside |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38227032 | Derived | Courtright KR, Madden V, Bayes B, Chowdhury M, Whitman C, Small DS, Harhay MO, Parra S, Cooney-Zingman E, Ersek M, Escobar GJ, Hill SH, Halpern SD. Default Palliative Care Consultation for Seriously Ill Hospitalized Patients: A Pragmatic Cluster Randomized Trial. JAMA. 2024 Jan 16;331(3):224-232. doi: 10.1001/jama.2023.25092. | |
| 27348271 | Derived | Courtright KR, Madden V, Gabler NB, Cooney E, Small DS, Troxel A, Casarett D, Ersek M, Cassel JB, Nicholas LH, Escobar G, Hill SH, O'Brien D, Vogel M, Halpern SD. Rationale and Design of the Randomized Evaluation of Default Access to Palliative Services (REDAPS) Trial. Ann Am Thorac Soc. 2016 Sep;13(9):1629-39. doi: 10.1513/AnnalsATS.201604-308OT. |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D007676 | Kidney Failure, Chronic |
| D003704 | Dementia |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| Duration of hospital stay, an expected average of 8 days |
| Dyspnea assessment | Documented assessments of patients' dyspnea within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Code status | Code status documented within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Mechanical ventilation | Documented orders for mechanical ventilation within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Cardiopulmonary resuscitation | Documented orders for cardiopulmonary resuscitation within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Inpatient dialysis | Documented orders for dialysis during inpatient stay within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| ICU admission | Transferal to an intensive care unit documented within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Hospital discharge status | Hospital discharge disposition code documented within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Discharge planning orders | Discharge orders for home care services documented within the electronic health record | Duration of hospital stay, an expected average of 8 days |
| Hospital readmission | 30-day hospital re-admissions documented within the Premier database | 30 days |
| Direct cost per day | Direct cost per day documented within the Premier database | Duration of hospital stay, an expected average of 8 days |
| Direct cost per hospitalization | Direct cost per hospitalization documented within the Premier database | Duration of hospital stay, an expected average of 8 days |
| Jacksonville |
| Florida |
| 32204 |
| United States |
| St. Vincent's Medical Center, Southside | Jacksonville | Florida | 32216 | United States |
| Via Christi Hospital, St. Francis | Wichita | Kansas | 67214 | United States |
| Via Christi Hospital, St. Joseph | Wichita | Kansas | 67218 | United States |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | United States |
| Our Lady of Lourdes Memorial Hospital | Binghamton | New York | 13905 | United States |
| St. Thomas West Hospital | Nashville | Tennessee | 37205 | United States |
| University Medical Center Brackenridge | Austin | Texas | 78701 | United States |
| Columbia St. Mary's, Ozaukee | Mequon | Wisconsin | 53097 | United States |
| Columbia St. Mary's, North Lake | Milwaukee | Wisconsin | 53211 | United States |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D051436 | Renal Insufficiency, Chronic |
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |