The Effect of Non Invasive Electrical Stimulation Therapy on Gastroesophageal Reflux Disease (GERD) Symptoms - Proof of Concept Study

The Effect of Non Invasive Electrical Stimulation Therapy on Gastroesophageal Reflux Disease (GERD) Symptoms - Proof of Concept Study

The aims of the study: To evaluate whether the use of a specific TENS technology can improve GERD symptoms and esophageal acid exposure.

Inclusion Criteria:

• at least 3 episodes of heartburn and/or regurgitation in a week for at least 3 months.
• evidence for an abnormal esophagal acid exposure on impedance-pH monitoring (tested in the last 2 years off PPI)

Exclusion Criteria:

• gastric or esophagal surgery
• active peptic ulcer disease
• malignancy
• pregnancy
• uncontrolled diabetes mellitus
• severe cardiac conditions such as cardiac arrhythmia or ischemia or cardiac pacemaker/defibrillator
• allergy to adhesives/patches
• severe pulmonary disease
• obesity (BMI>30)