Comparison of Two Marketed Silicone Hydrogel Lenses

One Month Clinical Comparison of Lotrafilcon B and Samfilcon A

The purpose of this study is to evaluate cholesterol sorption by AIR OPTIX® AQUA lenses compared to ULTRA lenses after 30 days of wear.

Inclusion Criteria:

• Sign informed consent document;
• Vision correctable to 20/40 Snellen (feet) or better in each eye at distance with both study contact lenses;
• Willing to wear study lenses on a daily basis (minimum 5 days/week, 8 hours/day) and attend all study visits;
• Successful wear of single-vision spherical, 2-week/ monthly replacement silicone hydrogel contact lenses in both eyes daily wear during the past 2 months for a minimum of 5 days/week, 8 hours/day. (Note: Monovision is included);
• Other protocol-specified inclusion criteria may apply.

Exclusion Criteria:

• Any anterior segment infection, inflammation, disease or abnormality that contraindicates contact lens wear (within 7 days of enrollment, or current);
• History of herpetic keratitis, corneal surgery or irregular cornea;
• Any use of systemic or ocular medications within the past 30 days for which contact lens wear could be contraindicated as determined by the investigator;
• Monocular (only 1 eye with functional vision) or fit with only one lens;
• Current or past AIR OPTIX® AQUA or ULTRA lens wearers;
• Other protocol-specified exclusion criteria may apply.