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The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
All outpatient patients were found to have >3 cm uterine myoma or adenomyosis were invited to participate in this study. The size and location of uterine myoma or adenomyosis and the uterus should be assessed by ultrasonography. Besides, all enrolled female patients will be asked to complete overactive bladder symptom score, female bladder function (UDI-6 & IIQ-7), female sexual function index, and bowel incontinence assessment questionnaires. In addition, patients who underwent surgeries for myoma or adenomyosis will be requested to complete the above questionnaires at 3 months after surgery. Women with intact uterus should be assessed again by ultrasonography. At least 30 women with age and body mass index matched and without uterine myoma or adenomyosis will be invited to participate in this study as the control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women with uterine myoma | Women with uterine myoma |
| |
| Women with adenomyosis | Women with adenomyosis |
| |
| Women without uterine myoma or adenomyosis | Control group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| myomectomy or adenomyomectomy | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| The corrleation coefficient between the size of myoma and Overactive Bladder Symptoms Scores | The Spearman's correlation between the size of uterine myoma and the score of Overactive Bladder Symptoms Scores | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The corrleation coefficient between the size of myoma and the presence of constipation/diarrhea | The Spearman's correlation between the size of uterine myoma and the presence of constipation/diarrhea | 12 weeks |
| Comparison of Overactive Bladder Symptoms Scores between the adenomyosis group and the control group |
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<Women with myoma or adenomyosis>
Inclusion Criteria:
<The control group>
Inclusion criteria:
<Both groups>
Exclusion Criteria:
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Women with uterine myoma or adenomyosis
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sheng-Mou Hsiao, MD | Contact | +89667000 | 1818 | smhsiao2@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Sheng-Mou Hsiao, MD | Department of Obstetrics & Gynecology, Far Eastern Memorial Hospital, Banqiao, New Taipei, Taiwan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Far-Eastern Memorial Hospital | Recruiting | Banqiao District | New Taipei | 22050 | Taiwan |
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| ID | Term |
|---|---|
| D062788 | Adenomyosis |
| D047708 | Myofibroma |
| D059411 | Lower Urinary Tract Symptoms |
| D012735 | Sexual Dysfunction, Physiological |
| ID | Term |
|---|---|
| D014591 | Uterine Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| ID | Term |
|---|---|
| D063186 | Uterine Myomectomy |
| ID | Term |
|---|---|
| D013509 | Gynecologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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Comparison of Overactive Bladder Symptoms Scores between the adenomyosis group and the control group by Wilcoxon rank-sum test |
| 12 weeks |
| Comparisons of the constipation/diarrhea rates between the adenomyosis group and the control group | Comparisons of the constipation/diarrhea rates between the adenomyosis group and the control group by Chi-square test or Fisher's exact test | 12 weeks |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D009372 | Neoplasms, Connective Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |