Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Canadian Optometric Education Trust Fund (COETF) | UNKNOWN |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Tears play a vital role in vision. A thin layer of tears is always present to cover the surface of the eye for optimal comfort and vision. There are several layers to the tear film, and the outer most layer is comprised of lipids. This lipid layer prevents evaporation of the tears and may be disrupted in people suffering from symptoms of dry eye. Cleaning eyelids with Cliradex wipes have shown to be effective in reducing dry eye symptoms in some patients, and the purpose of this study is to evaluate the tear film lipid layer thickness before and after one months treatment with Cliradex Wipes.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment | Experimental | Participants clean their eyelids with Cliradex wipes before going to bed at night. |
|
| Control | No Intervention | No treatment |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cliradex | Other | Cliradex is simply water and 4-Terpineol, a natural organic compound found Melaleuca alternifolia. The other ingredients in Cliradex are in less than 1% of the formulation and are Glycerin, Polysorbate 20, Polysorbate 80, Carbomer, Triethanolamine. |
| Measure | Description | Time Frame |
|---|---|---|
| Lipid layer thickness | Lipid layer thickness measured in nm. | Baseline |
| Lipid layer thickness | Lipid layer thickness measured in nm. | 1 month after baseline visit. |
| Measure | Description | Time Frame |
|---|---|---|
| Non-invasive tear breakup time (NITBUT) | Measurement of time taken for a dry spot to appear on the corneal surface after blinking. | Baseline |
| Non-invasive tear breakup time (NITBUT) | Measurement of time taken for a dry spot to appear on the corneal surface after blinking. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Lyndon Jones, PhD | CCLR, University of Waterloo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre for Contact Lens Research, University of Waterloo | Waterloo | Ontario | N2L 3G1 | Canada |
Not provided
| ID | Term |
|---|---|
| D015352 | Dry Eye Syndromes |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 1 month after baseline visit. |
| Dry Eye Questionnaire (SPEED score) | Standard Patient Evaluation of Eye Dryness questionnaire. Assessment of subjects' frequency and severity of dry eye symptoms. The total score was calculated as the sum scores for all symptoms over a range of 0 to 28. A lower total SPEED score represents less frequent and/or less severe symptoms. | Baseline |
| Dry Eye Questionnaire (SPEED score) | Standard Patient Evaluation of Eye Dryness questionnaire. Assessment of subjects' frequency and severity of dry eye symptoms. The total score was calculated as the sum scores for all symptoms over a range of 0 to 28. A lower total SPEED score represents less frequent and/or less severe symptoms. | 15 days after baseline visit. |
| Dry Eye Questionnaire (SPEED score) | Standard Patient Evaluation of Eye Dryness questionnaire. Assessment of subjects' frequency and severity of dry eye symptoms. The total score was calculated as the sum scores for all symptoms over a range of 0 to 28. A lower total SPEED score represents less frequent and/or less severe symptoms. | 1 month after baseline visit. |
| Overall corneal staining grade | Overall corneal staining score evaluated on a scale from 0 (none) to 5 (severe). A lower grade indicates less corneal surface desiccation. | Baseline |
| Overall corneal staining grade | Overall corneal staining score evaluated on a scale from 0 (none) to 5 (severe). A lower grade indicates less corneal surface desiccation. | 1 month after baseline visit. |
| Conjunctival hyperemia | Conjunctival hyperemia evaluated on a scale from 0 (negligible) to 100 (severe). | Baseline |
| Conjunctival hyperemia | Conjunctival hyperemia evaluated on a scale from 0 (negligible) to 100 (severe). | 1 month after baseline visit. |