Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers

Evaluation of Efficacy and Safety of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers: a Randomized, Double-blind, Placebo-controlled, Parallel-group Clinical Trial

The purpose of this study is to assess the efficacy and safety of a cashew apple extract on weight management and associated metabolic risk factors in overweight/obese volunteers, versus placebo, after 12 weeks of treatment.

Inclusion Criteria:

• 27 ≤ BMI ≤ 35 kg/m²
• Abdominal obesity
• Acceptance to adhere to diet and physical activity recommendations while maintaining global lifestyle habits
• Stable body weight (<5% variation) within the last 3 months prior to screening

Exclusion Criteria:

• Allergy to nuts and products thereof and allergy to mango fruit
• Type I or II diabetes
• Smokers
• Severe chronic diseases
• History of bariatric surgery and eating disorders
• Use of weight management products or medications which could affect nutrients absorption, lipids or carbohydrates metabolism