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| Name | Class |
|---|---|
| Beijing Chao Yang Hospital | OTHER |
| Beijing Jishuitan Hospital | OTHER |
| Beijing Luhe Hospital | OTHER |
| Qingdao Municipal Hospital |
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The purpose of this study is to evaluate the disease burden of hospitalized patients with CAP and healthcare-associated pneumonia (HCAP) in real life of China .
In China, the data about current management of patients hospitalized with CAP in the real-life setting is not available,type of pneumonia, selection of initial antibiotic, time to clinical stability, antibiotic choice anf modification,clinical outcomes and costs remain unclear.
In this study, we will collect comprehensive information on CAP and HCAP management patterns to evaluate the disease burden of hospitalized patients with CAP and HCAP in real life of China .to analyze microbiological characteristics,clinical manifestations,antibiotic regimens ,adherences to guidelines and effect on outcome in different groups of patients with CAP (> and = 65 years, different comorbidities ,risk factors) ,to investigate microbiological characteristics,clinical manifestations,antibiotic regimens ,adherences to guidelines and effect on outcome in different groups of disease severity with CAP ,to provide the difference on microbiological characteristics,clinical manifestations,antibiotic regimens ,and outcome between patients with CAP and HCAP ,to understand the current situation of antibiotic regimen ,to evaluate influence of different antibiotic regimens on prognosis.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| other | Other | retrospective cohort study |
| Measure | Description | Time Frame |
|---|---|---|
| treatment failure at 72h after initiation of antibiotics | treatment failure was defined as a change of antibiotics due to worsening signs or symptoms associated with pneumonia | Time from the first dose use of antibiotics to 72 hours |
| in-hospital treatment failure due to multiple causes | 1)death in hospital;2)change of antibiotics due to worsening signs or symptoms of infection, 3) recurrence, defined as signs or symptoms of infection after completion of therapy requiring re-initiation of antibiotics | Time from date of admission to discharge up to 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of intravenous antimicrobial therapy | Time from the first dose of intravenous antibiotics to date of stop of intravenous antibiotics ,participants will be followed for the duration of hospital stay | 2 weeks |
| Hospital length of stay |
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Inclusion Criteria:
Exclusion Criteria:
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3000 patients with community acquired pneumonia who meet the below inclusion/ exclusion criteria will be recruited in China.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bin Cao, MD | Contact | 86-010-84206264 | caobin_ben@163.com | |
| LI Gu, MD | Contact | 86-010-85231514 | guli2013227@foxmail.com.cn |
| Name | Affiliation | Role |
|---|---|---|
| Bin Cao, MD | China-Japan Friendship Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| China-Japan Friendship Hospital | Recruiting | Beijing | 100029 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24106842 | Result | Yang SQ, Qu JX, Wang C, Yu XM, Liu YM, Cao B. Influenza pneumonia among adolescents and adults: a concurrent comparison between influenza A (H1N1) pdm09 and A (H3N2) in the post-pandemic period. Clin Respir J. 2014 Apr;8(2):185-91. doi: 10.1111/crj.12056. Epub 2013 Nov 26. | |
| 24551881 | Result | Cao B, Huang GH, Pu ZH, Qu JX, Yu XM, Zhu Z, Dong JP, Gao Y, Zhang YX, Li XH, Liu JH, Wang H, Xu Q, Li H, Xu W, Wang C. Emergence of community-acquired adenovirus type 55 as a cause of community-onset pneumonia. Chest. 2014 Jan;145(1):79-86. doi: 10.1378/chest.13-1186. |
| Label | URL |
|---|---|
| Related Info | View source |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Apr 25, 2016 | |
| Unrelease | Yes | |
| Release | May 7, 2016 | |
| Reset | Jun 13, 2016 | |
| Release | Jun 20, 2016 | |
| Reset | Aug 1, 2016 | |
| Release | Nov 11, 2016 | |
| Reset | Jan 9, 2017 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Apr 25, 2016 | Yes | |||
| May 7, 2016 |
| ID | Term |
|---|---|
| D000098968 | Community-Acquired Pneumonia |
| ID | Term |
|---|---|
| D017714 | Community-Acquired Infections |
| D007239 | Infections |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
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| OTHER |
| Qilu Hospital of Shandong University | OTHER |
| Beijing Huimin Hospital | UNKNOWN |
| China-Japan Friendship Hospital | OTHER |
| Linzi Hospital | UNKNOWN |
| Second Hospital of Beijing Armed Police Corps | UNKNOWN |
| Kunming Yan'an Hospital | UNKNOWN |
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Patients will be asked about hospitalization, date, Patients will be asked about hospitalization, date, participants will be asked about the time of admission and discharge
| 2 weeks |
| in-hospital mortality | Time from date of admission to date of discharge,participants will be followed for the duration of hospital stay | 2 weeks |
| 23578215 | Result | Qu J, Gu L, Wu J, Dong J, Pu Z, Gao Y, Hu M, Zhang Y, Gao F, Cao B, Wang C; Beijing Network for Adult Community-Acquired Pneumonia (BNACAP). Accuracy of IgM antibody testing, FQ-PCR and culture in laboratory diagnosis of acute infection by Mycoplasma pneumoniae in adults and adolescents with community-acquired pneumonia. BMC Infect Dis. 2013 Apr 11;13:172. doi: 10.1186/1471-2334-13-172. |
| 38111015 | Derived | Han X, Wang H, Chen L, Wang Y, Li H, Zhou F, Xing X, Zhang C, Suo L, Wang J, Yu G, Wang G, Yao X, Yu H, Wang L, Liu M, Xue C, Liu B, Zhu X, Li Y, Xiao Y, Cui X, Li L, Liu X, Cao B. Impact of inhaled corticosteroid use on elderly chronic pulmonary disease patients with community acquired pneumonia. Chin Med J (Engl). 2024 Jan 20;137(2):241-243. doi: 10.1097/CM9.0000000000002936. Epub 2023 Dec 20. No abstract available. |
| 32919458 | Derived | Han X, Liu X, Chen L, Wang Y, Li H, Zhou F, Xing X, Zhang C, Suo L, Wang J, Yu G, Wang G, Yao X, Yu H, Wang L, Liu M, Xue C, Liu B, Zhu X, Li Y, Xiao Y, Cui X, Li L, Cao B; CAP-China network. Disease burden and prognostic factors for clinical failure in elderly community acquired pneumonia patients. BMC Infect Dis. 2020 Sep 12;20(1):668. doi: 10.1186/s12879-020-05362-3. |
| 29699493 | Derived | Han X, Zhou F, Li H, Xing X, Chen L, Wang Y, Zhang C, Liu X, Suo L, Wang J, Yu G, Wang G, Yao X, Yu H, Wang L, Liu M, Xue C, Liu B, Zhu X, Li Y, Xiao Y, Cui X, Li L, Purdy JE, Cao B; CAP-China network. Effects of age, comorbidity and adherence to current antimicrobial guidelines on mortality in hospitalized elderly patients with community-acquired pneumonia. BMC Infect Dis. 2018 Apr 24;18(1):192. doi: 10.1186/s12879-018-3098-5. |
| 29449294 | Derived | Chen L, Zhou F, Li H, Xing X, Han X, Wang Y, Zhang C, Suo L, Wang J, Yu G, Wang G, Yao X, Yu H, Wang L, Liu M, Xue C, Liu B, Zhu X, Li Y, Xiao Y, Cui X, Li L, Uyeki TM, Wang C, Cao B; CAP-China network. Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey. BMJ Open. 2018 Feb 15;8(2):e018709. doi: 10.1136/bmjopen-2017-018709. |
| Related Info | View source |
| Related Info | View source |
| Jun 13, 2016 |
| Jun 20, 2016 | Aug 1, 2016 |
| Nov 11, 2016 | Jan 9, 2017 |
| D012140 |
| Respiratory Tract Diseases |