The Best Dosage and Timing of Polyethylene Glycol for Bowel Preparation Before Capsule Endoscopy

The Best Dosage and Timing of PEG for Bowel Preparation Before Capsule Endoscopy a Prospective, Single-Blind, Randomized, Multi-center Study

The aim of this study is to evaluate the ideal dose of PEG and timing of bowel preparation in patients referred for CE examination.

Inclusion Criteria:

• Patients aged between 18 and 75 years and referred to capsule endoscopy because of suspected small-bowel disease are prospectively eligible for entry into the study.

Exclusion Criteria:

• Age < 18 or > 75 years
• Known or suspected GI stricture or fistula
• A history of GI tract resection
• Swallowing disorders
• Intensive therapy with fasting and parenteral nutrition;with a disease that may reduce movement of the GI tract, such as diabetes mellitus
• Medications that could affect gastrointestinal movement within one week
• Implanted with a medical electronic device
• Active inflammatory bowel disease, toxic megacolon, toxic colitis
• Severe pulmonary, cardiac, renal, or hepatic disease
• Uncontrolled hypertension (systolic blood pressure>170 mm Hg, diastolic blood pressure>100 mm Hg);
• Disturbance of electrolytes
• Pregnancy or lactation
• Patients inability to provide written voluntary informed consent
• Participation in another clinical study