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Fecal Incontinence (FI) is a debilitating and common condition with a prevalence ranging from 7-15% in community dwelling women. FI has an immense impact on quality of life and is associated with increased care giver burden, increased rates of institutionalization, and significant cost burden in older women. Traditionally believed to be primarily caused by child birth injury, recent studies show that the typical age of onset of FI is age 40 which is remote from child birth. Treatment options for FI are limited because the mechanism underlying FI in older women are poorly understood. The overriding goal of this project is to investigate the relationship between diet, stool metabolites and fecal incontinence.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fecal incontinence | Women age >18 years old with a diagnosis of fecal incontinence |
| |
| Controls | Women age >18 without a diangosis of fecal incontinence |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No Intervention | Other | No intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| Stool butyrate levels | within 1 week of collection | |
| Pattern of dietary intake by indicator | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Stool levels of global metabolites | within 1 week of collection |
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Inclusion Criteria:
Exclusion Criteria:
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Women with fecal incontinence from an outpatient GYN clinic.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States |
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| ID | Term |
|---|---|
| D005242 | Fecal Incontinence |
| ID | Term |
|---|---|
| D012002 | Rectal Diseases |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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