EFFECT OF Salvia Hispanica l. (CHIA) IN THE BIOCHEMICAL METABOLIC SYNDROME COMPONENTS

EFFECT OF Salvia Hispanica L. ( CHIA ) IN THE BIOCHEMICAL METABOLIC SYNDROME COMPONENTS IN PATIENTS IN THE NATIONAL MEDICAL CENTER WEST OF THE MEXICAN SOCIAL SECURITY INSTITUTE

The objective of this study is to evaluate the effect of the administration of 25 g of chia per day, for 90 days on the biochemical components of the metabolic syndrome in subjects with this condition

The metabolic syndrome (MS) is a cardiovascular risk factor and is present in about 20-25% of the world's adult population. Individuals with this condition have twice the risk of cardiovascular disease and die from it, compared with those who do not and 5 times more likely to develop type 2 diabetes mellitus (DM2). For this reason, it is appropriate to develop better tools for prevention and management of MS, with more emphasis on lifestyle´s changes. Chia has been studied in the past 10 years due to its high concentration of omega-3 alpha-linolenic acid (ALA) and 6 linoleic acid (LA) showing beneficial effects in some components of MS in rodents and individuals. The addition of chia to the conventional treatment of MS for the modification of metabolic disorders provides us a tool for easy incorporation into daily life, inexpensive and accessible in our environment.

Inclusion Criteria:

• Diagnosis of metabolic syndrome according to Adult Treatment Panel - III criteria.
• Subject wishing to participate in the study by written consent.
• Instituto Mexicano del Seguro Social beneficiaries subject
• Subject who not requiring modification of medical treatment for MS in the recruitment period.

Exclusion Criteria:

• Chronic renal failure with filtration glomerular rate clearance less than 30ml / min.
• Diabetic neuropathy.
• Post menopause
• Intestinal malabsorption diseases .
• Type 2 diabetes with HbA1c > 8.5 %
• Systolic and diastolic blood pressure >140/90 mmHg.
• Triglycerides > 300 mg/dL.
• LDL cholesterol >160mg/dL.
• Systemic autoimmune diseases .
• Cirrhosis or liver failure .
• Subject infected with human immunodeficiency virus or acquired immunodeficiency syndrome .
• Diagnosis of cancer with active disease.
• Subject previously undergoing bariatric surgery.
• Pregnancy or lactation.
• Alcoholism and drug addiction.
• Subject who consume high fiber dietary supplements and / or omega 3 acids.
• Subject taking anorexic drugs.
• Subject under diet for weight loss implemented by a health professional.