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Postoperative ileus (POI) is a common problem after major abdominal surgery. Acupuncture is being accepted in the West as a treatment option for managing POI and various functional gastrointestinal disorders. Therefore, we conducted a prospective randomized pilot study to evaluate the effect of electro-acupuncture on POI and other surgical outcomes in patients who underwent gastric surgery for a later large-scale study.
Before surgery, patients were randomized (using simple randomization) to either acupuncture (A) group or non-acupuncture (NA) group. In both groups, sitz markers were inserted in duodenum or jejunum during surgery for detection of postoperative remnant sitz markers by Xray. In the A group, acupuncture treatment was given once daily for up to 5 consecutive days starting on postoperative day 1. The acupuncture points which were used were based on traditional Korean medicine. No acupuncture treatment was performed in the NA group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Acupuncture | Experimental | The patients who were received acupuncture after gastric cancer surgery |
|
| Non-acupuncture | No Intervention | The patients who were not received acupuncture after gastric cancer surgery |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| acupuncture | Device | Acupuncture treatment after gastric cancer surgery during 5 postoperative days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Remnant sitz markers in small intestine at postoperative day 1 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 1. | measured in postoperative day 1 |
| Remnant sitz markers in small intestine at postoperative day 3 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 3. | measured in postoperative day 3 |
| Remnant sitz markers in small intestine at postoperative day 5 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 5. | measured in postoperative day 5 |
| Remnant sitz markers in small intestine at postoperative day 7 | Numbers of of remnant sitz markers in the small intestine that did not pass through ileo-cecal valve, measured by X-ray on postoperative day 7. | measured in postoperative day 7 |
| Measure | Description | Time Frame |
|---|---|---|
| Time to first flatus | up to 5 dyas | |
| start of water intake | up to 7days | |
| start of soft diet |
| Measure | Description | Time Frame |
|---|---|---|
| white blood cell count in preoperative period | measured in day before operation | |
| white blood cell count in postoperative day 1 | measured in postoperative day 1 | |
| white blood cell count in postoperative day 3 |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hyun-dong Chae, Professor | Department of Surgery, School of Medicine, Catholic University of Daegu | Study Director |
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| ID | Term |
|---|---|
| D045823 | Ileus |
| D013274 | Stomach Neoplasms |
| ID | Term |
|---|---|
| D007415 | Intestinal Obstruction |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D015670 | Acupuncture Therapy |
| ID | Term |
|---|---|
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
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| up to 7days |
| hospital stay | up to 2 weeks |
| measured in postoperative day 3 |
| white blood cell count in postoperative day 5 | measured in postoperative day 5 |
| white blood cell count in postoperative day 7 | measured in postoperative day 7 |
| serum C reactive protein level in preoperative period | measured in day before operation |
| serum C reactive protein level in postoperative day 1 | measured in postoperative day 1 |
| serum C reactive protein level in postoperative day 3 | measured in postoperative day 3 |
| serum C reactive protein level in postoperative day 5 | measured in postoperative day 5 |
| serum C reactive protein level in postoperative day 7 | measured in postoperative day 7 |
| serum albumin level in preoperative period | measured in day before operation |
| serum albumin level in postoperative day 1 | measured in postoperative day 1 |
| serum albumin level in postoperative day 3 | measured in postoperative day 3 |
| serum albumin level in postoperative day 5 | measured in postoperative day 5 |
| serum albumin level in postoperative day 7 | measured in postoperative day 7 |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D013272 | Stomach Diseases |