The purpose of this study is to evaluate the role of routine Staging Laparoscopy in patients with potentially resectable pancreatobiliary cancer.

To evaluate the role of routine staging laparoscopy in patients with potentially resectable pancreatobiliary cancer. All analyses are performed using SAS version 9.1.3 for Windows (SAS institute, Cary, NC). Clinical and pathological variables will be analyzed using the χ2 test (or Fisher's exact test) and the Student's t test, depending on the normality of the distribution. P-values of < 0.05 are considering statistically significant.

Inclusion Criteria:

1. Resectable pancreatobiliary cancer confirmed by radiologic studies (CT scan, MRI, PET-CT)

2. No evidence of distant metastasis

3. aged 15-80 year old

4. performance status (PS) of 0 or 1 on Eastern Cooperative Oncology Group (ECOG) scale

5. adequate organ functions defined as indicated below

   1. WBC 3000 ~ 12 000/mm3
   2. > Hb 8.0 g/dl
   3. > Plt 100 000/mm3
   4. < Cr 1.2 mg/dl
   5. > Ccr 60 ml/min/body

Exclusion Criteria:

1. cystic neoplasm, neuroendocrine tumors

2. pregnant or breast-feeding women

3. previous upper abdominal surgery except laparoscopic cholecystectomy 4.Serious illness in medical condition

   1. unstable angina or myocardial infarction within 6 months of the trial
   2. unstable hypertension
   3. congestive heart failure
   4. severe respiratory disease requiring continuous oxygen therapy
   5. liver failure
   6. systemic administration of corticosteroids
   7. severe mental disorder