Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
To compare APACHE II and P-POSSUM scoring system in emergency laparotomy.
To compare APACHE II and P-POSSUM scoring system in predicting postoperative mortality in patients undergoing emergency laparotomy.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Area Under the Receiver Operating Curve (ROC) as a Measure of the Accuracy of the APACHE II and P-POSSUM Scoring Systems to Predict Mortality | Participants will be followed for the duration of hospital stay (expected average of 30 days) and mortality was noted.All patients undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 were included in the study. All patients were scored with APACHE II and P-POSSUM scoring systems on the day of surgery. Area under the curve (AUC) is used to measure the "size" of the prediction composed by the graphic display between the 'sensitivity' and the '1-specificity' relationship. AUC can range from 0.5 to 1.0 and a result of 1.0 indicates a perfect discriminatory ability. An AUC value > 0.8 is considered good, a range between 0.60-0.80 is considered as moderate, and an AUC value < 0.60 is regarded as poor. For APACHE-II, a cut off score of >/=24 was determined; for P-POSSUM, a cut off score of >/= 63 was determined. | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Length of Stay (LOS) | The mean duration of hospital stay or Length of Stay was recorded | 30 days |
| Need for Postoperative Ventilator Support | Number of patients needing post-operative ventilatory support |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
All patients undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 will be included in the study. All patients will be scored with APACHE II and P-POSSUM scoring systems on the day of surgery.The patients will be followed up till discharge, death or 30 days postoperatively.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Ankur Dembla, DA | Tata Main Hospital, Jamshedpur, India | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tata Main Hospital | Jamshedpur | Jharkhand | 831001 | India |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31531317 | Result | Nag DS, Dembla A, Mahanty PR, Kant S, Chatterjee A, Samaddar DP, Chugh P. Comparative analysis of APACHE-II and P-POSSUM scoring systems in predicting postoperative mortality in patients undergoing emergency laparotomy. World J Clin Cases. 2019 Aug 26;7(16):2227-2237. doi: 10.12998/wjcc.v7.i16.2227. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
All who underwent emergency exploratory laparotomy from December 2013 to November 2014 at the Tata Main Hospital, Jamshedpur, India who met the inclusion criteria were included in the study
Not provided
| ID | Title | Description |
|---|---|---|
| FG000 | All Patients Who Underwent Emergency Exploratory Laparotomy | All patients who underwent emergency exploratory laparotomy from December 2013 to November 2014 at the Tata Main Hospital, Jamshedpur, and met the inclusion criteria were scored using the P-POSSUM Score APACHE-II |
| Title | Milestones | Reasons Not Completed | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
|
Not provided
Not provided
| ID | Title | Description |
|---|---|---|
| BG000 | Emergency Laparotomy | All patients who underwent emergency exploratory laparotomy from December 2013 to November 2014 at the Tata Main Hospital, Jamshedpur, and met the inclusion criteria were scored using the APACHE-2 Score & P-POSSUM Score |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Customized | All patients above 18 years age were included in the study |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Area Under the Receiver Operating Curve (ROC) as a Measure of the Accuracy of the APACHE II and P-POSSUM Scoring Systems to Predict Mortality | Participants will be followed for the duration of hospital stay (expected average of 30 days) and mortality was noted.All patients undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 were included in the study. All patients were scored with APACHE II and P-POSSUM scoring systems on the day of surgery. Area under the curve (AUC) is used to measure the "size" of the prediction composed by the graphic display between the 'sensitivity' and the '1-specificity' relationship. AUC can range from 0.5 to 1.0 and a result of 1.0 indicates a perfect discriminatory ability. An AUC value > 0.8 is considered good, a range between 0.60-0.80 is considered as moderate, and an AUC value < 0.60 is regarded as poor. For APACHE-II, a cut off score of >/=24 was determined; for P-POSSUM, a cut off score of >/= 63 was determined. | All patients undergoing emergency laparotomy at Tata Main Hospital form December 2013 to November 2014 were scored with APACHE II & P-POSSUM scoring systems on the day of surgery. The patients were followed up till at least 30 days after discharge or death (during admission or within 30 days after discharge). | Posted | Number | 95% Confidence Interval | probability of accurate prediction | 30 days |
The patients were followed up for the duration of admission and till at least 30 days after discharge or death (whichever was earlier).
Not provided
Not provided
| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | APACHE-2 Scoring | All patients undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 were included in the study. All patients were scored with APACHE II on the day of surgery. |
Not provided
Not provided
Observational study. So no specific adverse effect because of the study.
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Dr.Deb Sanjay Nag | Tata Main Hospital | +91-7763807101 | debsanjay@gmail.com |
Not provided
Not provided
Not provided
Not provided
| 30 days |
| Need for Post Operative Inotropic Support | Number of patients needing post-operative inotropic support | 30 days |
| Cardiac Morbidity (AMI or Arrhythmias Needing Treatment) | Number of patients noted to have Cardiac morbidity: Acute myocardial infarction (AMI) or arrhythmias needing treatment | 30 days |
| Number of Participants With Acute Kidney Injury (AKI) | Acute Kidney Injury (AKI) was diagnosed based on the Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group (2012) guidelines
| 30 days |
| Patients Needing Re-exploration | Number of patients needing return to the operation theater for surgery for the same pathology or any other complication arising out of the initial surgery | 30 days |
| Number |
| participants |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
|
|
|
|
|
| Secondary | Length of Stay (LOS) | The mean duration of hospital stay or Length of Stay was recorded | Posted | Mean | Standard Deviation | Days | 30 days |
|
|
|
| Secondary | Need for Postoperative Ventilator Support | Number of patients needing post-operative ventilatory support | Posted | Number | participants | 30 days |
|
|
|
| Secondary | Need for Post Operative Inotropic Support | Number of patients needing post-operative inotropic support | Posted | Number | participants | 30 days |
|
|
|
| Secondary | Cardiac Morbidity (AMI or Arrhythmias Needing Treatment) | Number of patients noted to have Cardiac morbidity: Acute myocardial infarction (AMI) or arrhythmias needing treatment | Posted | Number | participants | 30 days |
|
|
|
| Secondary | Number of Participants With Acute Kidney Injury (AKI) | Acute Kidney Injury (AKI) was diagnosed based on the Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group (2012) guidelines
| Posted | Number | participants | 30 days |
|
|
|
| Secondary | Patients Needing Re-exploration | Number of patients needing return to the operation theater for surgery for the same pathology or any other complication arising out of the initial surgery | Posted | Number | participants | 30 days |
|
|
|
| 0 |
| 157 |
| 0 |
| 157 |
| EG001 | P-POSSUM | All patients undergoing emergency laparotomy at Tata Main Hospital form 01st December 2013 to 30th November 2014 were included in the study. All patients were scored with P-POSSUM on the day of surgery | 0 | 157 | 0 | 157 |
Not provided
Not provided
Not provided