Translation, Cross-cultural Adaptation and Validation of the MGQOL-15-F

Translation, Cross-cultural Adaptation and Validation of the MGQOL-15-F

The purpose of this study is to translate and culturally adapt the MGQOL-15 (health-related quality of life scale for myasthenia gravis) for use with French-speaking patients in France and to evaluate its psychometric properties to ensure reliability and validity.

It is a translation and validation of a quality of life scale.

Step 1: Translation and cultural adaptation (Forward and back translation, committee review, pre-testing with 10 patients for content and face validity).

Step 2 : Psychometric testing : Test-retest with a 2 day interval, correlation with clinical scores - the Myasthenic Muscle Score and the (MG-ADL) score and with a global quality of life score (WHOQOL-BREF).

Inclusion Criteria:

• Auto-immune myasthenia gravis
• Age ≥ 18 years old
• Clinical Classification (MGFA) I-IV
• French speaking

Exclusion Criteria:

• cognitive or visual impairment which would limit the capacity to fill out the MGQOL-15-F