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To determine efficacy and safety of Sipjeondaebo-tang for Cancer patients suffering from anorexia after chemotherapy. Sipjeondaebo-tang will be administered for 4 weeks, 3 times per day after a meal. Changes of FAACT scale, Anorexia VAS, Weight, BMI, Clinical laboratory test such as ACTH, Cortisol, Chrelin, IL-6, ESR, CRP will be measured and analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SJDBT group | Experimental | Herbal medicine |
|
| Placebo | Placebo Comparator | Placebo control |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SJDBT | Drug | Sipjeondaebo-tang |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| The Functional Assessment of Anorexia/Cachexia Therapy - Anorexia Cachexia Subscale | Function scores as measured by the likert scale | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| FAACT scale | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chunhoo Cheon, Master | Institute of Safety and Efficiency Evaluation for Korean Medicine | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dunsan Korean Medicine Hospital | Daejeon | 302-869 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29441116 | Derived | Cheon C, Yoo JE, Yoo HS, Cho CK, Kang S, Kim M, Jang BH, Shin YC, Ko SG. Efficacy and Safety of Sipjeondaebo-Tang for Anorexia in Patients with Cancer: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial. Evid Based Complement Alternat Med. 2017;2017:8780325. doi: 10.1155/2017/8780325. Epub 2017 Dec 26. | |
| 27173813 | Derived |
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| Placebo | Drug | Placebo |
|
|
| Cheon C, Park S, Park YL, Huang CW, Ko Y, Jang BH, Shin YC, Ko SG. Sipjeondaebo-tang in patients with cancer with anorexia: a protocol for a pilot, randomised, controlled trial. BMJ Open. 2016 May 12;6(5):e011212. doi: 10.1136/bmjopen-2016-011212. |