To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

The study will be conducted on patients admitted to Department of Hepatology from MARCH 2015 to DECEMBER 2016 at ILBS, New Delhi.All patients presenting to ILBS fulfilling the inclusion criteria will be included in the study and will be categorized and evaluated. The patient will followed over a period of 3 months.

Inclusion Criteria:

• All consecutive patients presenting to hospital with bilirubin ≥5 and INR≥1.5
• Cirrhosis with or without Decompensation presenting with acute deterioration in less than 3 month

Exclusion Criteria:

• Cirrhosis with chronic decompensation.
• Patient on anticoagulant
• Hepatocellular carcinoma
• Septic shock
• Post-liver transplant or resection