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Inclusion according to criteria was not practical in our setting.
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Constipation is a common condition among patients with Guillain-Barré Syndrome. It is believed, that the constipation is caused by autonomic neuropathy. However, the severity of the constipation, and its relation to autonomic function have not previously been studied.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GBS Patients | Patients with Guillain-Barré syndrome |
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| Measure | Description | Time Frame |
|---|---|---|
| Gastrointestinal transit time (GITT) [in days] | The measurement takes one week to perform. The investigators aim to start the measurement within one week after diagnosis. |
| Measure | Description | Time Frame |
|---|---|---|
| Association between heart rate variability (HRV) and GITT | Linear regression with GITT as dependent variable, and high frequency power spectral density analysis of the heart rate (HF) as the independent variable. The mean HF of the first and second HRV measurement is used for this regression. | The first HRV measurement is performed within one week after diagnosis. The second is performed 7 days after the first. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients at Aarhus University Hospital, admitted with Guillain-Barré syndrome.
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| Name | Affiliation | Role |
|---|---|---|
| Henning Andersen, Professor, Dr. med. PhD | Aarhus University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aarhus University Hospital | Aarhus C | 8000 | Denmark |
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| ID | Term |
|---|---|
| D020275 | Guillain-Barre Syndrome |
| D003248 | Constipation |
| ID | Term |
|---|---|
| D011129 | Polyradiculoneuropathy |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
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| D011115 | Polyneuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D000094025 | Post-Infectious Disorders |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |