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| ID | Type | Description | Link |
|---|---|---|---|
| 2013/13098-9 | Other Grant/Funding Number | FAPESP |
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The aim of this study will be evaluate clinically the use of the Semilunar Coronally Positioned Flap (SCPF) for the treatment of gingival recessions, with or without Enamel Matrix Derivative (EMD). Thirty patients will be assigned in two groups. Half of patients will receive EMD associated to SCPF, while the other half, will receive SCPF alone.
The aim of this study will be evaluate clinically the use of the Semilunar Coronally Positioned Flap (SCPF) for the treatment of gingival recessions, with or without Enamel Matrix Derivative (EMD). Thirty patients will be selected, randomized and allocated in two groups: test group (SCPF + EMD) and control group (SCPF). The subjects will should present buccal Miller class I gingival recessions with height greater than or equal to 2.0 mm and less than to 4.0 mm in maxillary canines or premolars. Clinical parameters will be evaluated: gingival recession height (GRH), gingival recession width(GRW), clinical attachment level (CAL), probing depth (PD), height (HKT) and thickness (TKT) of keratinized tissue and papillas height (HP) and width(LP), as well as plaque and gingival index. These data will be collected at baseline and 180 days after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SCPF + EMD (TEST) | Experimental | Semilunar coronally positioned flap with Enamel matrix derivative (Emdogain) |
|
| SCPF (CONTROL) | Active Comparator | Semilunar coronally positioned flap alone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Semilunar coronally positioned flap | Procedure | Semilunar coronally positioned flap with enamel matrix derivative (Emdogain) or alone. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Recession Reduction as measured by difference between gingival recession depth | Measured as a difference between gingival recession depth at baseline and gingival recession at 6 months follow-up. | Baseline, 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Complete root coverage | Assessed as percentage of sites with complete root coverage | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Enilson A Sallum, PhD | University of Campinas, Brazil | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Piracicaba Dental School, State University of Campinas | Piracicaba | São Paulo | 13414-903 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29948276 | Derived | Franca-Grohmann IL, Sangiorgio JPM, Bueno MR, Casarin RCV, Silverio KG, Nociti FH Jr, Casati MZ, Sallum EA. Does enamel matrix derivative application improve clinical outcomes after semilunar flap surgery? A randomized clinical trial. Clin Oral Investig. 2019 Feb;23(2):879-887. doi: 10.1007/s00784-018-2506-y. Epub 2018 Jun 12. |
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| Enamel matrix derivative (Emdogain) | Device | Enamel matrix derivative associated to semilunar coronally positioned flap (SCPF + EMD - test group) |
|
| ID | Term |
|---|---|
| D005889 | Gingival Recession |
| ID | Term |
|---|---|
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D055093 | Periodontal Atrophy |
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