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| Name | Class |
|---|---|
| Clienia Littenheid AG | OTHER |
| University of Zurich | OTHER |
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The main goal of the proposed project is to assess treatment-induced changes of electrophysiological and psychophysiological correlates of the capacity to regulate emotion, executive functions, and clinical measures in individuals with complex posttraumatic stress disorder and dissociative disorders in a naturalistic inpatient setting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patient group | Experimental | Inpatient setting (cPTSD, DDNOS, DIS): Trauma-adapted psychotherapy (individual and group setting), body-related, cognitive stabilization groups, pharmacotherapy, and other non-verbal treatment modalities (e.g. music, art, and occupational therapy) |
|
| healthy control group | No Intervention | passive control group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| therapeutic treatment (inpatient and outpatient setting) | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| event-related potential (ERP) | up to 6 months | |
| power in specific frequency bands | up to 6 month |
| Measure | Description | Time Frame |
|---|---|---|
| heart rate | up to 6 months | |
| electrodermal activity | up to 6 months | |
| executive function |
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Inclusion Criteria:
-ability to undergo EEG measurement/psychophysiological measurement
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Silke Bachmann, Prof. Dr. med. | Privat Clinic Clienia Littenheid | Study Director |
| Yolanda Schlumpf, PhD | Privat Clinic Clienia Littenheid, University of Zurich | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Privat Clinic Clienia Littenheid | Littenheid | Thurgau | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35966482 | Derived | Schlumpf YR, Nijenhuis ERS, Klein C, Jancke L, Bachmann S. Functional connectivity changes in the delta frequency band following trauma treatment in complex trauma and dissociative disorder patients. Front Psychiatry. 2022 Jul 25;13:889560. doi: 10.3389/fpsyt.2022.889560. eCollection 2022. | |
| 34105902 | Derived |
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| ID | Term |
|---|---|
| D009105 | Dissociative Identity Disorder |
| ID | Term |
|---|---|
| D004213 | Dissociative Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D007291 | Inosine Monophosphate |
| ID | Term |
|---|---|
| D007292 | Inosine Nucleotides |
| D011685 | Purine Nucleotides |
| D011687 | Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
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working memory, Schuhfried test battery
| up to 6 months |
| measurement of psychological symptoms | questionnaire, Brief Symptom Inventory (BSI) | up to 6 month |
| assessment of emotion regulation and dysregulation | questionnaire, Difficulties in Emotion Regulation Scale (DERS) | up to 6 month |
| Schlumpf YR, Nijenhuis ERS, Klein C, Jancke L, Bachmann S. Resting-state functional connectivity in patients with a complex PTSD or complex dissociative disorder before and after inpatient trauma treatment. Brain Behav. 2021 Jul;11(7):e02200. doi: 10.1002/brb3.2200. Epub 2021 Jun 9. |
| D000072471 |
| Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
| D009711 | Nucleotides |
| D009706 | Nucleic Acids, Nucleotides, and Nucleosides |
| D012265 | Ribonucleotides |