Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| The University of Hong Kong | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Diabetic macular oedema (DMO) is a sight-threatening problem for diabetic patient who has swelling in macula. Patients with DMO can receive laser treatment and achieve good acuity finally. However, some patients still have difficulties in reading even after proper treatment.
In this project, the investigators aimed to explore the effectiveness of different training paradigms in improving reading performance in patients with DMO.
Patients with diabetic macular oedema (DMO), after receiving laser photocoagulation, achieved good outcomes in distance acuity. However, some patients, particularly those developing parafoveal scotoma, still had difficulty in reading. Inability to read or reading very slowly leads to the potential loss of job, as well as the enjoyment of reading for leisure.
In this study, the investigators aimed to investigate the effectiveness of reading rehabilitation using perceptual learning paradigms in enhancing reading performance in patients with reading difficulties due to DMO. Also, the fundamental mechanisms explaining the reading problems in patients with DMO reading Chinese will be examined.
The investigators hypothesize that the perceptual training would show an improvement in reading. The investigators' primary hypothesis is that temporal visual processing speed and spatial visual span will be improved after perceptual training. The investigators' secondary hypothesis is that the reading speed and fixation stability will be improved after training.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Temporal Group | Active Comparator | Receive 6 weekly 1-hour training sessions by Trigrams (A tailor made reading-task training programme). |
|
| Spatial Group | Active Comparator | Receive 6 weekly 1-hour training sessions by Trigrams (A tailor made reading-task training programme). |
|
| Combined Group | Active Comparator | Receive 6 weekly 1-hour training sessions by Trigrams (A tailor made reading-task training programme). |
|
| Control Group | Placebo Comparator | Receive 6 weekly 1-hour training sessions of leisure reading activities |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Temporal Group | Other | Visual Processing Training |
| |
| Spatial Group |
| Measure | Description | Time Frame |
|---|---|---|
| Change in visual processing speed | Using trigrams to measure the character-recognition accuracy while characters are presented at different exposure times | Change from baseline at week 6 and change from baseline at week 12 week |
| Change in visual span size | Using trigrams to measure the character-recognition accuracy while characters are presented at different positions | Change from baseline at week 6 and change from baseline at week 12 week |
| Measure | Description | Time Frame |
|---|---|---|
| Change in reading performance | Measured in three different ways for Chinese:
| Change from baseline at week 6 and change from baseline at week 12 week |
| Change in fixation stability |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Allen Ming Yan Cheong, PhD | The Hong Kong Polytechnic University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Allen MY Cheong | Hong Kong | China |
Not provided
| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Other |
Spatial visual span training |
|
| Combined Group | Other | Visual processing speed and spatial visual span training |
|
| Control Group | Other | Leisure reading activities |
|
Fixation stability will be measured by MP-1 microperimeter. |
| Change from baseline at week 6 and change from baseline at week 12 week |
| Change in Chinese version of Impact of Visually Impaired (C-IVI) measure | Self evaluated instrument to measure vision related restriction of participation in daily living. | Change from baseline at week 6 and change from baseline at week 12 week |
| D008722 | Methods |