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The purpose of this study is to define the cause of renal stones and the risk pattern for recurrence of renal stones episodes (any kind of stones) in HIV1 patients.
This study aims at defining the cause of renal stones and the risk pattern for recurrence of renal stones episodes (any kind of stones) in HIV1 patients.
Primary Objective :
Secondary Objective(s)
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| Measure | Description | Time Frame |
|---|---|---|
| Qualitative assessment of the cause of the renal stone | Qualitative assessment of the cause of the renal stone based on different biological and clinical parameters (biochemical analysis of urines, cristalluria, low dose renal CT, patient history, family history…) | at 6 months |
| Risk profile for recurrence of renal stone | Risk profile for recurrence of renal stone estimated based on plasma and urinary parameters, nutritional profile and drug exposure | at 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Follow up outcome of HIV patients over one year to identify prevalence of recurrences and describe co-morbidities associated with stone disease | up to 12 months | |
| Urological management for renal stones in HIV patients | up to 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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Adult male or female HIV1 infected patients having experienced a renal stone episode within the past six months or living with a renal stone
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| Name | Affiliation | Role |
|---|---|---|
| corinne i bagnis | Groupe Hospitalier Pitie Salpetriere et Chaire de Recherche en Education Therapeutique | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Corinne Isnard Bagnis | Paris | 75013 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25904366 | Result | Abgrall S, Rachas A, Tourret J, Isnard-Bagnis C, Billaud E, Tattevin P, Costagliola D, Guiguet M, Durieux P; French Hospital Database on HIV. A multifaceted intervention designed to improve medical management of moderate to advanced chronic kidney disease in HIV-infected patients: a cluster randomized trial. Clin Infect Dis. 2015 Aug 1;61(3):375-84. doi: 10.1093/cid/civ310. Epub 2015 Apr 22. | |
| 24052632 |
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| ID | Term |
|---|---|
| D053040 | Nephrolithiasis |
| D056844 | Renal Colic |
| D000092162 | Crystalluria |
| D051436 | Renal Insufficiency, Chronic |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| Causes of drug induced renal stones | up to 12 months |
| Number of stone recurrences | at 6 months |
| Number of stone recurrences | at 12 months |
| Result |
| Tourret J, Deray G, Isnard-Bagnis C. Tenofovir effect on the kidneys of HIV-infected patients: a double-edged sword? J Am Soc Nephrol. 2013 Oct;24(10):1519-27. doi: 10.1681/ASN.2012080857. Epub 2013 Sep 19. |
| 21745806 | Result | Bige N, Lanternier F, Viard JP, Kamgang P, Daugas E, Elie C, Jidar K, Walker-Combrouze F, Peraldi MN, Isnard-Bagnis C, Servais A, Lortholary O, Noel LH, Bollee G. Presentation of HIV-associated nephropathy and outcome in HAART-treated patients. Nephrol Dial Transplant. 2012 Mar;27(3):1114-21. doi: 10.1093/ndt/gfr376. Epub 2011 Jul 10. |
| 19375399 | Result | Tourret J, Tostivint I, Deray G, Isnard-Bagnis C. [Kidney diseases in HIV-infected patients]. Nephrol Ther. 2009 Nov;5(6):576-91. doi: 10.1016/j.nephro.2009.02.007. Epub 2009 Apr 16. French. |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D052801 | Male Urogenital Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D020924 | Urological Manifestations |
| D051437 | Renal Insufficiency |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |