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| ID | Type | Description | Link |
|---|---|---|---|
| 22173 | Other Identifier | Temple IRB |
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| Name | Class |
|---|---|
| Shriners Hospitals for Children | OTHER |
| University of Delaware | OTHER |
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The purpose of this study is to investigate how sensory information processing affects balance ability in children with cerebral palsy (CP). An additional goal is to determine if a subsensory electrical stimulation called Stochastic Resonance (SR) Stimulation, can improve balance in children with CP. Children with CP and children with typical development will participate and complete a series of clinical and balance assessments. They will also be tested in a sensor fusion paradigm to investigate potential deficits in the dynamic integration of visual, vestibular and proprioceptive information during upright stance. SR stimulation will then be used to potentially improve these deficits and subsequently their balance ability.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Children with Cerebral palsy | Experimental |
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| Children with Typical Development | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sensory Integration Testing | Procedure | Investigate how sensory information are integrated during upright stance when visual and body senses are challenged in a virtual reality environment |
| Measure | Description | Time Frame |
|---|---|---|
| Gain response | For both the sensory reweighting testing, the visual signal will be displayed as a visual flow with translation in anterior-posterior (AP) direction (i.e., sagittal plane) and presented at different amplitudes (0.25 and 0.5 cm) at 0.2 Hz to measure: the change in gain (weighting) to vision (intramodal effect); and a change in gain to vibration and galvanic stimulation (intermodal effects). Gain for each modality relative to both the leg segment AP translation and trunk segment AP translation will be measured. | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Gain response | For the sensory reweighting with the addition of SR stimulation testing, the visual signal will be displayed as a visual flow with translation in anterior-posterior (AP) direction (i.e., sagittal plane) and presented at different amplitudes (0.25 and 0.5 cm) at 0.2 Hz to measure: the change in gain (weighting) to vision (intramodal effect); and a change in gain to vibration and galvanic stimulation (intermodal effects). Gain for each modality relative to both the leg segment AP translation and trunk segment AP translation will be measured. |
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Inclusion Criteria:
Exclusion Criteria:
Lower extremity surgery or fractures in the year prior testing
Joint instability or dislocation in the lower extremities
Botulinum toxin injections in the lower extremities within the past 6 months*
Marked visual or hearing deficits
Uncontrolled seizure disorder
Implanted medical device that may be contraindicated with application of SR stimulation
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anastasia Zarkou, PT, MS | Contact | azarkou@udel.edu | ||
| Samuel CK Lee, PT, PhD | Contact | slee@udel.edu |
| Name | Affiliation | Role |
|---|---|---|
| John Jeka, PhD | Temple University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Temple University | Recruiting | Philadelphia | Pennsylvania | 19122 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30526617 | Derived | Zarkou A, Lee SCK, Prosser LA, Hwang S, Jeka J. Stochastic resonance stimulation improves balance in children with cerebral palsy: a case control study. J Neuroeng Rehabil. 2018 Dec 10;15(1):115. doi: 10.1186/s12984-018-0467-7. |
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| ID | Term |
|---|---|
| D002547 | Cerebral Palsy |
| ID | Term |
|---|---|
| D001925 | Brain Damage, Chronic |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| SR stimulation & Sensory integration testing | Procedure | Use SR stimulation to improve sensory integration when visual and body senses are challenged in a virtual reality environment |
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| 1 day |
| Shriners Hospital for Children | Recruiting | Philadelphia | Pennsylvania | 19140 | United States |
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