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Recent evidence suggests that injection pressure monitoring may be able to predict needle nerve contact in the brachial plexus nerve block model, but little is known about multifascicular nerves. The investigators hypothesize that injection pressure monitoring can reliably predict needle-nerve contact during femoral nerve block.
Single center, observational study. Patients scheduled for elective lower limb surgery with femoral nerve block will be recruited. Femoral nerve will be identified using a linear ultrasound transducer. A 22 GA 5 cm nerve block needle will be inserted with bevel downward and advanced to the following conditions:
At each of these conditions, 1 ml of dextrose solution will be injected via an automated pump at 10 ml/min and the spread of injectate observed sonographically. Simultaneously, a blinded observer will measure opening injection pressure using both an electronic and a mechanical transducer. If opening pressure reaches 15 psi, this investigator will halt the injection. In addition, minimum threshold current required to elicit a motor response will be recorded for conditions 3 and 4. Patients will be contacted at 7 days and asked about any adverse effects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | A 22 GA 5 cm nerve block needle will be advanced to the following conditions:
At each of these conditions, 1 ml of dextrose solution will be injected and spread of injectate observed sonographically. A blinded observer will measure injection pressure. If opening pressure reaches 15 psi, this investigator will halt the injection. In addition, minimum threshold current required to elicit a motor response will be recorded for conditions 3 and 4. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Apposition of needle bevel against femoral nerve | Procedure | Indentation of femoral nerve and fascia iliaca by block needle and measurement of opening injection pressure during the controlled injection of 1 ml of dextrose (D5W) solution |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of high opening injection pressure (15 psi or greater) when needle tip in contact with nerve | 1 minute |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of high opening injection pressure (15 psi or greater) at other needle locations | 1 minute | |
| Minimum threshold current to elicit a motor response with needle-nerve contact and needle disengagement | 1 minute |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Malikah Latmore, MD | Mount Sinai St. Luke's Mount Sinai Roosevelt Hospitals | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St. Luke's-Roosevelt Hospital Center | New York | New York | 10025 | United States |
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| ID | Term |
|---|---|
| D009140 | Musculoskeletal Diseases |
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| Incidence of paresthesias | 1 week |