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The purpose of this study is to evaluate the safety and efficacy of nano drug interventional therapy using digital subtraction angiography(DSA) for lung cancer. The nano drug is made by mixing Gemzar® with Compound Glycyrrhizin Injection.
By enrolling patients with lung cancer adapted to enrolled criteria, this study will document for the first time the safety and the short and long term efficacy of nano drug interventional therapy using digital subtraction angiography(DSA)for lung cancer.
The nano drug is made by mixing Gemzar® with Compound Glycyrrhizin Injection. The nano drug's size is detected by laser diffraction particle size analyzer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nano drug | Experimental | Lung cancer patients received nano drug interventional therapy using digital subtraction angiography(DSA). The nano drug is made by mixing Gemzar® with Compound Glycyrrhizin Injection. |
|
| Drug MicroSpheres | Active Comparator | Lung cancer patients received drug microspheres (HepaSphere Microspheres) interventional therapy using digital subtraction angiography(DSA). |
|
| Control | No Intervention | Liver cancer patients never received any interventional therapy. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| interventional therapy | Procedure | Lung cancer patients received drug interventional therapy using the digital subtraction angiography(DSA.) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with Adverse events | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of lesions that show no sign of recurrence 12 months after interventional therapy | 1 year | |
| Progress free disease (PFS) | 1 year | |
| Overall survival (OS) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lizhi Niu, PhD | Fuda Cancer Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Central laboratory in Fuda cancer hospital | Guangzhou | Guangdong | 510000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23806858 | Background | Niu L, Chen J, Yao F, Zhou L, Zhang C, Wen W, Bi X, Hu Y, Piao X, Jiang F, Zeng J, Liu W, Li J, He L, Mu F, Zuo J, Xu K. Percutaneous cryoablation for stage IV lung cancer: a retrospective analysis. Cryobiology. 2013 Oct;67(2):151-5. doi: 10.1016/j.cryobiol.2013.06.005. Epub 2013 Jun 24. |
| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| 1 year |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |