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| Name | Class |
|---|---|
| Ministry of Health, Liberia | OTHER |
A cluster-randomized control trial will study the effect of insecticide-treated wall lining on malaria transmission in Bomi County, Liberia. Half of the villages enrolled in the study will receive insecticide-treated wall lining covering their walls and ceilings in addition to long-lasting insecticidal nets, while the other half will be protected by existing long-lasting insecticidal nets.
Long-lasting insecticidal nets (LLINs) are the established vector control product for malaria control. In Bomi County Liberia, LLINs have been distributed but malaria prevalence in children under 5 remains high, with prevalence in study villages found to be 42% in April 2014. The major malaria vector species are resistant to pyrethroid insecticides approved for use in LLINs, and new control measures with non-pyrethroid active ingredients may protect the population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | 21 clusters composed of one or more villages with a total number of 30 to 70 children under 5 years old. Routine distribution of long-lasting insecticidal nets is the only malaria control intervention. | |
| Intervention | Experimental | 21 clusters composed of one or more villages with a total of 30 to 70 children under 5 years old. Routine distribution of long-lasting insecticidal nets is available and in addition insecticide treated wall lining is installed in all sleeping areas with homeowner consent. All 4 walls and the ceiling are covered with lining. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Insecticide treated wall lining | Device | Polypropylene non-woven fabric. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Malaria Prevalence | Tested by mRDT and PCR | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Hemoglobin | Hemoglobin measured by Hemocue 301 | 6 months |
| Fever | Number of participants with Fever, defined as tympanic temperature above 37.5C |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| David J Giesbrecht, MSc | Study Coordinator | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bomi County Health Team | Tubmanburg | Bomi County | Liberia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36635660 | Derived | Giesbrecht D, Belleh TG, Pontarollo J, Hinneh VS, Pratt O, Kamal S, Allan R. Durable wall lining for malaria control in Liberia: results of a cluster randomized trial. Malar J. 2023 Jan 12;22(1):15. doi: 10.1186/s12936-022-04429-7. |
| Label | URL |
|---|---|
| The MENTOR Initiative | View source |
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| ID | Term |
|---|---|
| D016778 | Malaria, Falciparum |
| D000740 | Anemia |
| ID | Term |
|---|---|
| D008288 | Malaria |
| D011528 | Protozoan Infections |
| D010272 | Parasitic Diseases |
| D007239 | Infections |
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| 6 months |
| Mosquito biting rate. | Mosquitoes trapped indoors and outdoors using light traps and exit traps. | 2 months |
| D000096724 |
| Mosquito-Borne Diseases |
| D000079426 | Vector Borne Diseases |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |