Study of Association of Anti-inflammatory and Anti-rheumatic

Phase III Study Comparing Association of Anti-inflammatory and Anti-rheumatic

Phase III Study, double-blind, comparing association of anti-inflammatory and anti-rheumatic in 375 subjects with knee osteoarthritis.

Evaluation after 12 weeks of treatment, in 3 arms, the efficacy and safety of the association.

Inclusion Criteria:

• Signs the Informed Consent Form
• Age between 40 and 85 years
• osteoarthritis of the knee according to clinical and radiological criteria of the American College of Rheumatology

Exclusion Criteria:

• Cardiovascular disease
• Serious chronic comorbidity
• Hypersensitivity to any component of the study drugs
• body mass index> 30 kg / m²