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This study retrospectively assess the effect or using balanced hydroxyethyl sctarch (HES) 130/0.4 or a balanced crystalloid solution as a pump prime and for intraoperative fluid therapy on the risk of early acute postoperative kidney injury in adult cardiac surgery patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HES | Balanced HES 130/0.4 used as and pump prime and for intraoperative fluid therapy. |
| |
| Crystalloid | Balanced Crystalloid used as a pump prime and for intraoperative fluid therapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HES | Drug | 2500 mL of balanced HES 130/0.4 |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| AKIN SCr | Stage of acute kidney injury using the Acute Kidney Injury Network Classification omitting the diuresis criteria. | Forty eight hours |
| Measure | Description | Time Frame |
|---|---|---|
| AKIN SCr+UO | Stage of acute kidney injury using the Acute Kidney Injury Network Classification including the diuresis criteria. | Forty eight hours |
| Postoperative dialysis | Requirement of postoperative renal replacement therapy |
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Inclusion Criteria:
Exclusion Criteria:
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Adults patients undergoing cardiac surgery
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| ID | Term |
|---|---|
| D000077324 | Crystalloid Solutions |
| C048013 | Plasmalyte A |
| ID | Term |
|---|---|
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |
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| Crystalloid | Drug | 2500 mL of balanced crystalloid. |
|
|
| 30 days |
| Respiratory complication | Need for reintubation, non-invasive ventilation or prolonged intensive care unit stay as a consequence of atelectasis, pulmonary edema or pneumonia. | 30 days |
| ICU stay | Length of stay at the intensive care unit | 30 days |
| Hospital stay | Length of stay at the hospital | 30 days |
| 30-day mortality | Death in hospital or within 30 days of surgery | 30 days |