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The aim of this study is to evaluate the frequencey and the determinants of postpartum major complications (hemorrhage and thrombosis) up to 3 months after delivery in the maternity hospitals of Finistère (Bretagne - France)
This is an analytical observational prospective multicenter cohort study , conducted on all the maternity hospitals in Finistère (Bretagne - France), with a biological collection.
This protocol allows to study all women at risk of PPH (Postpartum Hemorrhage) and postpartum venous thromboembolic disease, including maternity level 1-3 without case selection. The prospective nature of the study should provide a more detailed analysis of exposures in this particular population of women (risk factors related to the field, childbirth, the postpartum events ...).
The events of interest were PPH and venous thromboembolic disease.
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| Measure | Description | Time Frame |
|---|---|---|
| Postpartum Hemorrhage | Volume of blood loss up to 48 hours after delivery and / or weight compresses collected at delivery, and / or diagnosis of the clinician | 2 days |
| Symptomatic thromboembolic events | 3 month |
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Inclusion Criteria:
Exclusion Criteria:
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All women admitted for delivery in a maternity Finistère
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| Name | Affiliation | Role |
|---|---|---|
| PAN PETESCH Brigitte | Unité d'Hémostase , Centre Régional de traitement de l'hémophilie et des maladies hémorragiques, CHRU de Brest (France) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CH de Carhaix | Carhaix-Plouguer | Finistère | 29270 | France | ||
| CHRU de Brest - Service de Gynécologie-obstétrique |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37343695 | Derived | Anouilh F, de Moreuil C, Tremouilhac C, Jacquot M, Salnelle G, Bellec V, Touffet N, Cornec C, Muller M, Dupre PF, Bellot C, Morcel K, Joliff DL, Drugmanne G, Gelebart E, Lucier S, Nowak E, Bihan L, Couturaud F, Tromeur C, Moigne EL, Pan-Petesch B. Family history of postpartum hemorrhage is a risk factor for postpartum hemorrhage after vaginal delivery: results from the French prospective multicenter Haemorrhages and Thromboembolic Venous Disease of the Postpartum cohort study. Am J Obstet Gynecol MFM. 2023 Sep;5(9):101062. doi: 10.1016/j.ajogmf.2023.101062. Epub 2023 Jun 19. |
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| ID | Term |
|---|---|
| D006473 | Postpartum Hemorrhage |
| D054556 | Venous Thromboembolism |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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Blood samples
| Brest |
| 29609 |
| France |
| Clinique Keraudren | Brest | France |
| CH de Landerneau | Landerneau | France |
| CH de Morlaix | Morlaix | France |
| CH Quimper | Quimper | France |
| D011644 | Puerperal Disorders |
| D014592 | Uterine Hemorrhage |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |