Brain Imaging Study

A Randomized, Double-blind, Placebo-controlled Study Investigating the Effects of a Proprietary Nutritional Supplement on Brain Health

The study is designed to evaluate the effects of the proprietary nutritional supplement on cognition, mood, and brain imaging parameters following a relatively short period of treatment.

Inclusion Criteria:

• Both male and female subjects will be included.
• Age between 40-60 years inclusive.
• Healthy subjects who, in the opinion of the investigator, are free of any medical conditions that might affect study measures.
• Eats 1 or fewer servings of fatty fish per week.
• BMI < 35

Exclusion Criteria:

• Current or past neurological illness.
• Substance abuse or dependence within the prior 60 days.
• Current depression (HAMD greater than 20) or anxiety disorder (HAMA greater than 18).
• Current or past history of psychiatric disorder.
• History of head trauma with loss of consciousness.
• Contraindication to brain MRI examination.
• Supplementation with Omega 3, fish oil, or other over the counter supplements including the other bioactive ingredients in the proprietary nutritional supplement, antioxidants and multi-vitamin mineral supplements for the previous 3 months.
• Plasma Omega3 Index >5% at screening visit.
• Subject has a known allergy or intolerance to any of the ingredients contained in the proprietary nutritional supplement or placebo.
• Subject is currently pregnant, planning to become pregnant, or is breastfeeding.