Evaluation of the Role of OCT in the Detection of HIV-associated Neurocognitive Disorder

Evaluation of the Role of Optical Coherence Tomography (OCT) in the Detection of HIV-associated Neurocognitive Disorder

The purpose of this study is to determine the sensitivity and specificity of the use of optical coherence tomography to detect HIV-associated neurocognitive disorder compared to MRI and usual cognitive screening tools.

Inclusion Criteria:

• HIV infection
• Antiretroviral treatment
• Undetectable plasmatic HIV viral load (viral load<50 copies/ml) for at least 6 months
• Ability to understand and give approved consent

Exclusion Criteria:

• Any present or past ophthalmologic illness that may impair OCT results
• Previous cerebral infection with sequel
• Previous cerebrovascular disease with sequel
• Severe psychiatric illness
• Active alcohol or drug abuse
• Active chronic hepatitis C
• Inability to perform french cognitive assessment
• Inability to perform a MRI
• Inability to perform a lumbar puncture