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The purpose of this observational epidemiological study is to investigate the management and the complications associated with severe trauma. Data will be analysed to answer pre-defined scientific projects and to improve management of these conditions.
Pseudonymized data will be collected by study coordinators in a secured e-database.
Cross audit will be performed to check data.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICU patients | Patients with severe trauma (with or without brain injury) or Patients with hemorrhagic shock Data concerning the ICU stay will be collected for these patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Collection of medical data from ICU patients | Other | A code will be applied to each patient included. Medical data such as demography, Simplified Acute Physiological Score II (SAPS II), Sequential Organ Failure Assessment (SOFA), procedures and complications during ICU stay will be collected. |
| Measure | Description | Time Frame |
|---|---|---|
| in ICU stay complications | Nosocomial Infections (epidemiology, risk factors, antibiotic susceptibility of pathogens) Organ failures (incidence, risk factors) Bleeding, hemorrhage Intra-cranial hypertension, brain ischemia Mechanical ventilation weaning, extubation failure | Within the 28 first days after ICU admission date |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of mechanical ventilation | in ICU (up to 90 days) | |
| ICU length of stay | in ICU (up to 90 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Death | in ICU (up to 90 days) |
Inclusion Criteria:
Exclusion Criteria:
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Patients hospitalized in ICU for severe trauma
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Karim Asehnoune, PhD, MD | Contact | 02 40 08 73 80 | 33 | karim.asehnoune@chu-nantes.fr |
| Antoine Roquilly, MD | Contact | 02 40 08 73 80 | 33 | antoine.roquilly@chu-nantes.fr |
| Name | Affiliation | Role |
|---|---|---|
| Karim ASEHNOUNE, PhD, MD | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Angers University Hospital | Recruiting | Angers | 49000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42204647 | Derived | Gourier S, Bouras M, Lakhal K, Launey Y, Leon K, Laffon M, Dahyot-Fizelier C, Roquilly A, Lasocki S, Langeron O, Caillard A; ATLANREA group. Impact of sex on outcomes in critically ill patients with subarachnoid hemorrhage: a secondary analysis of a French prospective cohort study. J Anesth Analg Crit Care. 2026 May 27. doi: 10.1186/s44158-026-00419-2. Online ahead of print. |
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| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
| D000070642 | Brain Injuries, Traumatic |
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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Plasma, sera, peripheral blood mononuclear cells, RNA
|
| Nantes University Hospital | Recruiting | Nantes | 44093 | France |
|
| Poitiers University Hospital | Recruiting | Poitiers | 86000 | France |
|
| Rennes University Hospital | Recruiting | Rennes | 35000 | France |
|
| Tours University Hospital | Recruiting | Tours | 37000 | France |
|
| D006259 |
| Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |