Effect of Topical Application of Iodex® Balm on Local Surface Temperature

An Exploratory Study to Assess the Effect of Topical Application of Iodex® Balm on Local Surface Temperature Using Infra Red Thermal Imaging Technique

The rationale of this study is to map out changes in temperature distribution brought about by topical application of our test product, and use this physiological phenomenon to visualize the onset of action involved in overall mechanism of action of the product.

Inclusion Criteria:

• Participants suffering from chronic osteoarthritis of knee joint (as per American College of Rheumatology criteria) for > 3 months
• Participants in good general and mental health with no clinically significant and relevant abnormalities of medical history or physical examination

Exclusion Criteria:

• Women of child bearing potential, pregnant and lactating women
• Intolerance/hypersensitivity to study material/ingredient
• Recent history of alcohol or drug abuse
• Participants receiving topical non-steroidal antiinflammatory drugs (NSAIDs), other topical analgesics/counterirritants/mineral oils, or other medication, which might interfere with study results
• Participants having psoriasis/active atopic dermatitis/eczema/skin infected lesions/burn/wound at the site of application