Measurement of the Retinal Oxygen Saturaiton After Long-term Silicon Oil Tamponade

Measurement of the Retinal Oxygen Saturaiton After Long-term Silicon Oil Tamponade With Oxymap

The purpose of this study is to evaluate the effects of long-term tamponade with silicone oil on retinal saturation with Oxymap.

Silicone oil is the first choice treatment for long-term vitreous replacement in complicated cases of retinal detachment. However, it will cause various problems for permanent tamponade, such as keratopathy, glaucoma, cataracts, and silicone oil emulsification3. In addition, silicone oil has the potential to cause retinal toxicity. Moreover, the gravity and mechanical pressure of the silicone oil on the retina may influence retinal blood flow and, and the presence of silicone oil in the vitreous cavity may block the oxygen exchange between the retinal surface and the vitreous humor, resulting in the metabolic disturbance of the retina. In this study, the investigators utilized a noninvasive measurement (Oxymap, Reykjavik, Iceland) to evaluate the effect of silicone oil tamponade on oxygen saturation and diameter in retinal vessels in complicated retinal detachment cases.

Inclusion Criteria:

• initial silicone oil tamponade duration of more than 3 months
• transparent reflecting media
• intraocular pressure (IOP) between 11 and 21mmHg
• complete retinal re-attachment
• healthy contralateral eye.

Exclusion Criteria:

• severe refractive media opacity (serious keratoleukoma and cataracts)
• silicone oil emulsification
• ocular hypertension
• retinal detachment
• retinal scar within the main vascular arch
• any ocular disease and any history of surgery in the contralateral eye
• any type of systemic disease
• pregnancy