Taste Evaluation of Different Liquid Formulations With Eliglustat

A Single-blind, Randomized, Unbalanced Crossover Design With 5 Vehicles, 5 Periods, and 5 Sequences, Repeated-doses (With no Ingestion) Study to Assess the Palatability of Eliglustat Prototype Liquid Formulations in Healthy Subjects

Primary Objective:

The purpose of this study is to assess the palatability of eliglustat prototype liquid formulations in healthy subjects.

The total duration of the study for each subject will be approximately 5 weeks (screening period from Day -28 to Day -2, treatment period of 3 days, and follow-up call on Day 5).

Inclusion criteria :

• Healthy male and female subjects, 18 to 55 years of age, inclusive.
• Normal smell and taste ability to discriminate odor and flavor differences.

Exclusion criteria:

• Poor metabolizer phenotype status for CYP2D6 (predicted based on genotype).
• Subject who has smoked within 3 months of inclusion.

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.