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Motive:
In order to improve the treatment technique, a comprehensive follow-up program is needed to obtain all relevant patient, treatment and toxicity data from lung cancer patients.
Goal:
To set-up and maintain a database containing treatment results in terms of tumor control, side effects, complications and patient-reported quality of life.
A standard database of patients receiving photon treatment will be created. These data are then linked to dose-volume data of radiotherapy, with the aim to build prediction models for both tumor control and toxicity after radio (chemo) therapy that can later be used for selecting patients for proton treatment.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Radiotherapy | Radiation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Acute toxicity | esophagitis (Common Terminology Criteria for Adverse Events, version 4.0) | Highest during and within 2 weeks after last day of radiation therapy |
| Late toxicity | esophagitis (Common Terminology Criteria for Adverse Events, version 4.0); pneumonitis (Common Terminology Criteria for Adverse Events, version 4.0) | Highest within one year after last day of radiation therapy |
| Measure | Description | Time Frame |
|---|---|---|
| Overall survival | at 1 year after first day of radiation therapy | |
| Overall survival | at 2 years after first day of radiation therapy | |
| Overall survival |
| Measure | Description | Time Frame |
|---|---|---|
| Patient-rated symptoms and Quality-of-Life | Within 1 week before or after last day of radiation therapy | |
| Patient-rated symptoms and Quality-of-Life | at 3 months after first day of radiation therapy | |
Inclusion Criteria:
Exclusion Criteria:
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Patients with Non-Small Cell Lung Cancer (NSCLC) or Small Cell Lung Cancer - Limited Disease (SCLC-LD) or thymoma or lungmetastases (treated with stereotactic radiotherapy), receiving radiotherapy dose > 40 Gy.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Robin Wijsman, MD PhD | Contact | +31503615532 | r.wijsman@umcg.nl |
| Name | Affiliation | Role |
|---|---|---|
| Robin Wijsman, MD | University Medical Center Groningen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Center Groningen | Recruiting | Groningen | Provincie Groningen | 9700RB | Netherlands |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D011878 | Radiotherapy |
| D059248 | Chemoradiotherapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
| D003131 | Combined Modality Therapy |
| D004358 | Drug Therapy |
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| at 3 years after first day of radiation therapy |
| Overall survival | at 4 years after first day of radiation therapy |
| Overall survival | at 5 years after first day of radiation therapy |
| Loco-regional tumor control | at 1 year after first day of radiation therapy |
| Loco-regional tumor control | at 2 years after first day of radiation therapy |
| Loco-regional tumor control | at 3 years after first day of radiation therapy |
| Patient-rated symptoms and Quality-of-Life |
| at 6 months after first day of radiation therapy |
| Patient-rated symptoms and Quality-of-Life | at one year after first day of radiation therapy |
| Patient-rated symptoms and Quality-of-Life | at 2 years after first day of radiation therapy |
| Patient-rated symptoms and Quality-of-Life | at 3 years after first day of radiation therapy |
| Patient-rated symptoms and Quality-of-Life | at 4 years after first day of radiation therapy |
| Patient-rated symptoms and Quality-of-Life | at 5 years after first day of radiation therapy |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |