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Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
As an improved MRI technique, diffusion-weighted imaging (DWI) is considered the most sensitive for early pathological changes. Perfusion measurement has been shown to improve sensitivity and predictive value for tumor grading and prognosis, also as a predicator of recovery with reperfusion in patients of acute ischemic stroke.Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Low b=(0,50,150,200)，NEX=(1,3,2,2) |
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| Group 2 | Low b=(0,30,50,100,200)，NEX=(1,3,3,2,2) |
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| Group 3 | Low b=(0,30,60,90,120,150,180,200)，NEX=(1,3,3,3,2,2,2,2) |
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| Group 4 | Low b=(0,30,60,90,120,150,180,200)，NEX=(1,1,1,1,1,1,1,1) | ||
| Group 5 | Low b=(0,20,40,60,80,100,120,140,160,180,200)NEX=(1,3,3,3,3,2,2 |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| different low b-values distribution | Other |
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| Measure | Description | Time Frame |
|---|---|---|
| Parameters D* and f in healthy white matter or gray mater | 2-3 days |
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Inclusion Criteria:
Exclusion Criteria:
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healthy volunteers
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