A Phase III, Open Label, Randomized Study of Atezolizumab (Anti-PD-L1 Antibody) Compared With a Platinum Agent (Cisplatin or Carboplatin) in Combination With Either Pemetrexed or Gemcitabine for PD-L1-Selected, Chemotherapy-Naive Patients With Stage IV Non-Squamous Or Squamous Non-Small Cell Lung Cancer
A Phase III, Open Label, Randomized Study of Atezolizumab (Anti-PD-L1 Antibody) Compared With a Platinum Agent (Cisplatin or Carboplatin) in Combination With Either Pemetrexed or Gemcitabine for PD-L1-Selected, Chemotherapy-Naive Patients With Stage IV Non-Squamous Or Squamous Non-Small Cell Lung Cancer
This randomized, open-label study will evaluate the efficacy and safety of atezolizumab compared with chemotherapy consisting of a platinum agent (cisplatin or carboplatin per investigator discretion) combined with either pemetrexed (non-squamous disease) or gemcitabine (squamous disease) in programmed death-ligand 1 (PD-L1)-selected, chemotherapy-naive participants with Stage IV Non-Squamous or Squamous NSCLC.
Inclusion Criteria:
Exclusion Criteria:
Nashville, Tennessee 37204, United States
Cachoeiro de Itapemirim, Espírito Santo 29308-014, Brazil
Ijuí, Rio Grande do Sul 98700-000, Brazil
Passo Fundo, Rio Grande do Sul 99010-260, Brazil
São Paulo, São Paulo 01246 000, Brazil
Thermi, Thessaloniki, 57001, Greece
Szolnok, 5004, Hungary
Meldola, Emilia-Romagna 47014, Italy
Aviano, Friuli Venezia Giulia 33081, Italy
Catania, Sicily 95123, Italy
Hokkaido, 060-8648, Japan
Satima, 362-0806, Japan
Olsztyn, 10-357, Poland
Timi?oara, 300210, Romania
Moscovskaya Oblast, Moscow Oblast 143423, Russia
Moscow, Moscow Oblast 105229, Russia
Saint Petersburg, Sankt-Peterburg 194017, Russia
Kazan', Tatarstan Republic 420029, Russia
Jeollanam-do, 58128, South Korea
Castellon de LA Plana/castello de LA Plana, Castellon 12002, Spain
Hat Yai, 90110, Thailand
Muang, 57000, Thailand
Izmir, 35110, Turkey (Türkiye)
Kharkiv, Kharkiv Governorate 61070, Ukraine
Odesa, Kherson Governorate 65055, Ukraine
Sumy, Kholm Governorate 40005, Ukraine
Dnipro, KIEV Governorate 49102, Ukraine
Kyiv, KIEV Governorate 02096, Ukraine
Vinnytsia, KIEV Governorate 21029, Ukraine
Lutsk, Volhynian Governorate 43018, Ukraine