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The purpose of this study is to retrospectively evaluate treatments and outcomes of patients with low grade serous ovarian carcinomas in Italy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single cohort | Retrospective analysis of all patients diagnosed, from 01/01/2000 to 01/01/2014, with low-grade serous ovarian cancer or invasive recurrence after surgery for borderline serous carcinoma |
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| Measure | Description | Time Frame |
|---|---|---|
| risk of recurrence in patients with low-grade serous ovarian carcinoma | two years | |
| number of patients with objective tumor response after receiving chemotherapy | 6 months | |
| number of patients with objective tumor response after receiving hormone therapy | 6 months | |
| number of patients with objective tumor response after receiving combination hormonal and chemotherapy | 6 months | |
| progression free survival | 2 years | |
| overall survival | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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patients diagnosed, from 01/01/2000 to 01/01/2014, with low-grade serous ovarian carcinoma or with invasive recurrence after surgery for borderline serous carcinoma
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Francesco Perrone, MD PhD | Contact | +39 081 5903571 | datamanager@usc-intnapoli.net | |
| Teresa Ribecco, PhD | Contact | +39 081 5903619 | teresa.ribecco@usc-intnapoli.net |
| Name | Affiliation | Role |
|---|---|---|
| Sandro Pignata, MD PhD | NCI Naples | Principal Investigator |
| Chiara Della Pepa, MD | NCI Naples | Principal Investigator |
| Francesco Perrone, MD PhD |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istitute Nazionale Tumori - Fondazione G. Pascale | Recruiting | Naples | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35869143 | Derived | Musacchio L, Califano D, Bartoletti M, Arenare L, Lorusso D, Losito NS, Cormio G, Greggi S, Raspagliesi F, Valabrega G, Salutari V, Pisano C, Spina A, Russo D, Del Sesto M, Canzonieri V, Ferrau F, Zannoni GF, Loizzi V, Ghizzoni V, Casanova C, Tuninetti V, Ducceschi M, Del Vecchio V, Scalone S, Priolo D, Perrone F, Scambia G, Pignata S. Clinical characteristics and molecular aspects of low-grade serous ovarian and peritoneal cancer: a multicenter, observational, retrospective analysis of MITO Group (MITO 22). Br J Cancer. 2022 Nov;127(8):1479-1486. doi: 10.1038/s41416-022-01897-1. Epub 2022 Jul 22. |
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Archival tissue tumor samples in paraffin blocks for evaluation of diagnosis and biomarkers
| NCI Naples |
| Principal Investigator |