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The aim of the study is to determine whether increasing the heart rate by epicardial atrial pacing after surgery improves the contractile force of the myocardium. After complete weaning from CPB, several pressure-loops of the LV will be recorded at different levels of preload using transoesophageal echo, invasive blood pressure monitoring. The preload will be manipulated by adding fluid from the CPB reservoir or draining fluid into the CPB reservoir.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Spontaneous rhythm first | Experimental | Stepwise preload increase by repeated administration of 100 mL of fluid during spontaneous rhythm and then stepwise preload reduction by repeated drainage of 100 mL of fluid during atrial pacing. |
|
| Atrial pacing first | Experimental | Stepwise preload increase by repeated administration of 100 mL of fluid during atrial pacing and then stepwise preload reduction by repeated drainage of 100 mL of fluid during spontaneous rhythm. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| External Pacing Box | Device | Atrial pacing using an external pacing box |
|
| Measure | Description | Time Frame |
|---|---|---|
| End-systolic elastane of the left ventricle. | 30 minutes after CPB weaning |
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Inclusion Criteria:
Exclusion Criteria:
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