An Open-Label Extension and Safety Monitoring Study of Patients With Moderately to Severely Active Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Protocol GA29144
An Open-Label Extension and Safety Monitoring Study of Patients With Moderately to Severely Active Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Protocol GA29144
This open-label extension and safety monitoring study is composed of two parts: Part 1 will evaluate the long-term safety and efficacy of continued etrolizumab treatment in participants with moderately to severely active Crohn's disease who were previously enrolled in the etrolizumab Phase III Study GA29144 (NCT02394028) and who meet eligibility criteria for enrollment into Part 1. In Part 2, participants who have stopped etrolizumab treatment (either by exiting Part 1 of this study or by entering directly from Study GA29144 [NCT02394028]) will be monitored for 92 weeks for progressive multifocal leukoencephalopathy (PML) and other safety events.
Inclusion Criteria:
Part 1 Open-Label Extension:
Part 2 Safety Monitoring:
Exclusion Criteria:
Part 1 Open-Label Extension:
Part 2 Safety Monitoring:
San Francisco, California 94158, United States
Spokane, Idaho 99202, United States
Kinston, North Carolina 28501, United States
Dallas, Texas 75390-9151, United States
CABA, C1199ABB, Argentina
Parkville, Victoria 3050, Australia
Prahan, Victoria 3181, Australia
Botucatu, São Paulo 18618-970, Brazil
Edmonton, Alberta T6G 2X8, Canada
Halifax, Nova Scotia B3H 1V7, Canada
Ottawa, Ontario K1H 1A2, Canada
Ostrava - Poruba, 708 52, Czechia
R?ga, LV-1002, Latvia
Riga, LV-1005, Latvia
Vilnius, 08661, Lithuania
Sittard-Geleen, 6162 BG, Netherlands
Bia?ystok, 15-275, Poland
Toru?, 87-100, Poland
Wroc?aw, 50-220, Poland
Wroc?aw, 52-210, Poland
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Bern, 3012, Switzerland
Kozyata?i, 34742, Turkey (Türkiye)
Kharkiv, Kharkiv Governorate 61037, Ukraine
Kharkiv, Kharkiv Governorate 61204, Ukraine
Kyiv, KIEV Governorate 1023, Ukraine
Kyiv, KIEV Governorate 2091, Ukraine
Odesa, 65059, Ukraine