Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to assess the impact of the Multi Point Pacing (MPP) feature in the treatment of patients with QRS beetwen 100 and 130 msec in patients candidate to ICD implant.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MPP ON | Experimental | Patients will be randomized to the MPP-ON Arm vs Standard ICD |
|
| Standard ICD | Active Comparator | Patients will be randomized to the MPP-ON Arm vs Standard ICD |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MultiPoint Pacing ON | Device | MultiPoint Pacing ON |
| |
| Implantable cardioverter-defibrillator (ICD) |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients presenting reverse remodeling (reduction of ESV > 15%) after 6 and 12 months | up to 12 Months |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients presenting reverse remodeling (reduction of ESV > 15%) after 24 months | 24-Months | |
| Percentage of responder patients in term of increase of EF > 5 points % at 12 months Follow-Up | 12-Months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Maurizio Gasparini, MD | Contact | maurizio.gasparini@humanitas.it |
| Name | Affiliation | Role |
|---|---|---|
| Maurizio Gasparini, MD | Humanitas Research Hospital-Rozzano-Italy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ospedale Maggiore di Crema | Crema | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27927248 | Derived | Gasparini M, Galimberti P, Bragato R, Ghio S, Raineri C, Landolina M, Chieffo E, Lunati M, Mulargia E, Proclemer A, Facchin D, Rordorf R, Vicentini A, Marcantoni L, Zanon F, Klersy C. Multipoint Pacing versus conventional ICD in Patients with a Narrow QRS complex (MPP Narrow QRS trial): study protocol for a pilot randomized controlled trial. Trials. 2016 Dec 3;17(1):572. doi: 10.1186/s13063-016-1698-1. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D017147 | Defibrillators, Implantable |
| ID | Term |
|---|---|
| D047548 | Defibrillators |
| D004566 | Electrodes |
| D055615 | Electrical Equipment and Supplies |
| D004864 | Equipment and Supplies |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Device |
Implantable cardioverter-defibrillator (ICD) |
|
| Percentage of responder patients in term of increase of EF > 5 points % at 24 months Follow-Up | 24-Months |
| Percentage of responder patients in term of BNP < 400 pg/ml at 12 months | 12 Months |
| A.O. Niguarda Ca' Granda | Milan | 20162 | Italy |
|
| Fondazione IRCCS Policlinico San Matteo | Pavia | 27100 | Italy |
|
| Ospedale S.Maria della Misericordia | Rovigo | Italy |
|
| Humanitas Research Hospital | Rozzano | Italy |
|
| Ospedale Santa Maria della Misericordia | Udine | Italy |
|
| D004567 |
| Electrodes, Implanted |
| D019736 | Prostheses and Implants |