Multi-electrodes Set for Deep Brain Stimulation in Parkinson Disease

Implantation Feasibility Study of a Multi-electrodes Set for Deep Brain Stimulation in Parkinson Disease (Smart in Vivo 2)

This study aims to demonstrate innocuity and feasibility of deep brain stimulation with a multi-electrodes set.

Bilateral stimulation in subthalamic nucleus with the multi-electrodes set will be compared with single electrode.

Inclusion Criteria:

• more or equal than 18 years old and less than 70 years
• patient affiliated to social security or similarly regime
• informed consent form signed
• parkinson disease (UPDRS III20 score up than 30/108 except for severe tremors)
• motor and non motor dysfunctions
• pre-operative cerebral MRI without lesion
• without chirurgical contraindications
• without psychiatric disease

Exclusion Criteria:

• Pregnant women and lactating mothers
• Ward of court or under guardianship
• Adult unable to express their consent
• Person deprived of freedom by judicial or administrative decision
• Person hospitalized without their consent
• Person under legal protection
• Person with carcinological antecedent during precedent 5 years
• Chirurgical or MRI contraindications