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| Name | Class |
|---|---|
| Pfizer | INDUSTRY |
| M-Health Solutions | UNKNOWN |
| Bristol-Myers Squibb | INDUSTRY |
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The ASSERT-III study aims to determine the incidence of sub-clinical (silent) atrial fibrillation (AF) among elderly patients with hypertension and at least one other risk factor for AF. This will be accomplished by monitoring with a wireless external loop monitor for 30 to 60 days.
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| Measure | Description | Time Frame |
|---|---|---|
| Occurance of atrial fibrillation episode | Detection rate of sub-clinical atrial fibrillation episodes, at least 6 minutes in duration | within 30 - 60 days of follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Tolerability and feasibility of long term monitoring in elderly patients | The tolerability of long-term monitoring in elderly patients and the ability of these patients to manually transmit data to the cardiac analyses centre. | 30 - 60 days of follow-up |
| Proportion of patients eligible to receive anticoagulation |
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Inclusion Criteria:
Patients will be eligible for inclusion if they meet all of the following:
Age ≥ 80 years
History of hypertension OR a blood pressure of ≥ 140/90 mmHg
Attending a primary care clinic, OR ambulatory resident of a chronic care facility
At least one of the following additional risk factors for developing AF:
Provide written informed consent
Exclusion Criteria:
ECG documented history of AF or atrial flutter, with an episode duration ≥ 6 minutes
Existing implanted pacemaker or defibrillator
Patients considered by the investigator to be unsuitable for study follow-up because the patient:
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elderly patients attending primary care clinic or ambulatory resident of a chronic care facility, with hypertension and at least one addional risk factor for developing AF.
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| Name | Affiliation | Role |
|---|---|---|
| Jeff Healey, M.D. | Population Health Research Institute | Principal Investigator |
| Stuart Connolly, M.D. | Population Health Research Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AVIVA Medical Diagnostics and Specialist Clinic Inc. | Burlington | Ontario | L7R 1E2 | Canada | ||
| Hamilton Medical Research Group |
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| 30 - 60 days of follow-up |
| AF Burden | An estimate of the burden of atrial arrhythmias (from device logs) in patients with AF. | 30 - 60 days of follow-up |
| Hamilton |
| Ontario |
| L8M 1K7 |
| Canada |
| Family Practice - Drs. Cameron, Crombie & Croft | Hamilton | Ontario | Canada |
| OakMed Family Health Team | Oakville | Ontario | L6H 7S8 | Canada |
| ID | Term |
|---|---|
| D006973 | Hypertension |
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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