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| ID | Type | Description | Link |
|---|---|---|---|
| 5R01MH094633-04 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
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This study examines the way attention may be linked to temperamental risk for anxiety, social behavior and brain processes. The study aims to see if temperamentally at risk youth display an attention bias towards threat, and if anxiety symptoms can be reduced through attentional bias modification training.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ABM | Experimental | Attention bias modification |
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| Placebo | Placebo Comparator | Dot-probe task |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Attention Bias Modification | Behavioral | This is a modification of the dot-probe task (placebo task) designed to train attention away from threat |
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| Measure | Description | Time Frame |
|---|---|---|
| Anxiety Symptoms | parent and child report of child's anxiety symptoms | 8 weeks |
| Attention bias levels | performance on computerized attention task | 8 weeks |
| Electrophysiological and neural correlates of attention bias | EEG and fMRI measures | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Penn State University Child Study Center | University Park | Pennsylvania | 16801 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24283271 | Background | LoBue V, Perez-Edgar K. Sensitivity to social and non-social threats in temperamentally shy children at-risk for anxiety. Dev Sci. 2014 Mar;17(2):239-47. doi: 10.1111/desc.12110. Epub 2013 Nov 28. | |
| 19108817 | Background | McDermott JM, Perez-Edgar K, Henderson HA, Chronis-Tuscano A, Pine DS, Fox NA. A history of childhood behavioral inhibition and enhanced response monitoring in adolescence are linked to clinical anxiety. Biol Psychiatry. 2009 Mar 1;65(5):445-8. doi: 10.1016/j.biopsych.2008.10.043. Epub 2008 Dec 24. |
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| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
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| Dot-probe task | Behavioral | This is the active control placebo condition that simply measures levels of attention to threat |
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| 20873921 | Background | Perez-Edgar K, McDermott JN, Korelitz K, Degnan KA, Curby TW, Pine DS, Fox NA. Patterns of sustained attention in infancy shape the developmental trajectory of social behavior from toddlerhood through adolescence. Dev Psychol. 2010 Nov;46(6):1723-30. doi: 10.1037/a0021064. |
| 21318555 | Background | Perez-Edgar K, Reeb-Sutherland BC, McDermott JM, White LK, Henderson HA, Degnan KA, Hane AA, Pine DS, Fox NA. Attention biases to threat link behavioral inhibition to social withdrawal over time in very young children. J Abnorm Child Psychol. 2011 Aug;39(6):885-95. doi: 10.1007/s10802-011-9495-5. |
| 17376704 | Background | Perez-Edgar K, Roberson-Nay R, Hardin MG, Poeth K, Guyer AE, Nelson EE, McClure EB, Henderson HA, Fox NA, Pine DS, Ernst M. Attention alters neural responses to evocative faces in behaviorally inhibited adolescents. Neuroimage. 2007 May 1;35(4):1538-46. doi: 10.1016/j.neuroimage.2007.02.006. Epub 2007 Feb 15. |
| 19521761 | Background | Williams LR, Degnan KA, Perez-Edgar KE, Henderson HA, Rubin KH, Pine DS, Steinberg L, Fox NA. Impact of behavioral inhibition and parenting style on internalizing and externalizing problems from early childhood through adolescence. J Abnorm Child Psychol. 2009 Nov;37(8):1063-75. doi: 10.1007/s10802-009-9331-3. |
| 29413142 | Derived | Liu P, Taber-Thomas BC, Fu X, Perez-Edgar KE. Biobehavioral Markers of Attention Bias Modification in Temperamental Risk for Anxiety: A Randomized Control Trial. J Am Acad Child Adolesc Psychiatry. 2018 Feb;57(2):103-110. doi: 10.1016/j.jaac.2017.11.016. Epub 2017 Nov 28. |