Utilization of iMRI for Transsphenoidal Resection of Pituitary Macroadenomas

A Single-center, Prospective, Randomized Controlled Trial Investigating the Utility if Intraoperative MRI in Transphenoidal Pituitary Surgery Off Macroadenomas.

The investigators are studying the utility of intra-operative magnetic resonance imaging (iMRI) during transsphenoidal pituitary surgery for large macroadenomas by randomizing patients to either an intra-operative MRI after resection, or no intra-operative MRI. The investigators will then count the number of gross total resection in each group of patients and also the complications related to surgery.

Inclusion Criteria:

• Adults 18-90

• Capable of giving informed consent

• Elect for transsphenoidal surgery

• Has pre-operative MRI demonstrating pituitary tumor that is:

  1. deemed resectable using a transsphenoidal approach and
  2. has a maximal diameter equal to or greater than 15 mm.

• No contraindications for MRI.

Exclusion Criteria:

• Children (age < 18)
• Not able to give consent
• No pituitary tumor visible on MRI or an adenoma measuring less than 15mm in maximal dimension.
• Unable to tolerate MRI