Efficacy on Helicobacter Pylori Eradication With Two Antibiotic Regimens

Efficacy on Helicobacter Pylori Eradication With Sequential Antibiotic Compared to Triple Therapy for 14 Days

Clinical trial to compare efficacy on eradicating Helicobacter pylori with two antibiotic strategies: sequential with amoxicillin and omeprazole 5 days and clarithromycin with metronidazole and omeprazole 5 days or omeprazole with clarithromycin and amoxicillin 14 days.

In patients with documented infection with Helicobacter pylori after endoscopy and biopsy, two modalities of treatment were compared, and after a control endoscopy and biopsy, eradication was assessed as well as side effects of both treatments.

Inclusion Criteria:

• Helicobacter pylori infection in biopsy
• Eradication required

Exclusion Criteria:

• Antibiotic received two weeks prior
• Previous treatment for H pylori infection
• Allergy to any of the treatment drugs
• Smoking > 5 cigarettes daily.