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The aim of study is to compare triple tourniquet vs. single tourniquet to reduce blood loss at open myomectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single tourniquet | Active Comparator |
| |
| Triple tourniquet | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Single tourniquet | Procedure | Single tourniquet is tourniquet applied uterine isthmus to occlude the uterine arteries. For this purpose, a small opening is made in the avascular place of the broad ligament on either side of the uterine isthmus superior to the uterine vessels. A pediatric Foley catheter is threaded through the two holes and tied tightly anteriorly around the cervix at the level of the internal os. |
| Measure | Description | Time Frame |
|---|---|---|
| Estimated blood loss at the end of myomectomy | Surgical blood loss will be estimated by sum of the volume of suction fluid and blood loss quantitated by gravimetric method. Suction fluid will be measured at the end of operation and volume of irrigation fluid will be subtracted from total suction volume. â—¦Surgical drapes, sponges and towels will be weighted before and just after surgery. The blood loss will be estimated as differences in gram by weighing when 1ml blood supposed as 1.06 gr. | 15 minutes postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| The amount of transfusions | Erythrocyte transfusions will be allowed when haemoglobin dropped below 8 g/dL. | 7 Days |
| A change in hemoglobin | At baseline and 48 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Anti-Mullerian Hormone levels variation | Anti-Mullerian Hormone levels before surgery, 6 months and 12 months after surgery | One year postoperatively |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Neset Gümüsburun, MD | Ataturk University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Atatürk Üniversitesi Araştırma Hastanesi | Erzurum | 25240 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37672088 | Derived | Gumusburun N, Yapca OE, Ozdes S, Al RA. Triple vs. single uterine tourniquet to reduce hemorrhage at myomectomy: a randomized trial. Arch Gynecol Obstet. 2023 Dec;308(6):1811-1816. doi: 10.1007/s00404-023-07201-7. Epub 2023 Sep 6. |
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| ID | Term |
|---|---|
| D047708 | Myofibroma |
| ID | Term |
|---|---|
| D009372 | Neoplasms, Connective Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D014111 | Tourniquets |
| ID | Term |
|---|---|
| D004864 | Equipment and Supplies |
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|
| Triple tourniquet | Procedure | Triple tourniquet consist of two tourniquet applied both infundibulopelvic ligaments and one uterine isthmus to occlude the left and right ovarian vessels and to occlude the uterine arteries. For this purpose, a small opening is made in the avascular place of the broad ligament on either side of the uterine isthmus superior to the uterine vessels. A pediatric Foley catheter is threaded through the two holes and tied tightly anteriorly around the cervix at the level of the internal os. Through the same openings in the broad ligament each side a Foley catheter looped around the infundibulopelvic ligament lateral to the fallopian tube and ovary. |
|
| Volume in drains | Drain will be removed when discharge drops below 50 ml/day | 7 days |
| Peri-operative complications | Including but not limited to fever, pelvic infections, wound infections. | 6 weeks |
| Total operation time | Skin to skin operation time | 5 minutes post operatively |
| Tourniquet time | 5 minutes after tourniquet removed |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |