The purpose of this study is to assess the effect of LEO 130852A gel 1% in maintaining skin thickness in healthy skin treated with steroid.

Inclusion Criteria:

• Healthy male volunteers, 25 to 50 years old inclusive
• Healthy skin on volar arms with a hairless area sufficient for measurements

Exclusion Criteria:

• Clinical skin atrophy, telangiectasia or striae on volar arms
• Presence of any skin condition or colouration that would interfere with test sites or the response or assessment
• Fitzpatrick skin type IV - VI
• History or current evidence of infection, eczema or other relevant skin disease