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Poor recruitment
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Depression and other unhealthy behaviors, such as not taking medication as prescribed and not attending doctor visits have been suggested to increase the worsening of allergic diseases (e.g. asthma, urticaria). We intend to determine whether a one-session behavioral intervention is effective in helping with depression and controlling disease symptoms. We will measure this using pre- and post-intervention surveys.
The purpose of this research study is to investigate whether a one-session behavioral activation intervention for depression can successfully reduce depression and improve asthma or urticaria disease-relevant outcomes (medication adherence, doctor's visits, substance abuse) in clinical patients with asthma or urticaria who report heightened levels of depression and are seen in the UMMC Allergy Clinic.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Brief Behavioral Activation Intervention | Experimental | All eligible participants will undergo the Brief Behavioral Activation Intervention. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Brief Behavioral Activation Intervention | Behavioral | Clinical psychologists (investigators) will instruct the participant in ways to become more active in life, particularly with regards to activities that the participant finds pleasurable and meaningful. The intervention will take one hour to complete. Following the intervention, the participant will receive brief, weekly text or email reminders for the next 4 weeks (total of 4) to engage in pleasurable and meaningful activities during the week. |
| Measure | Description | Time Frame |
|---|---|---|
| Asthma Control Test | Changes in asthma control over a 4 week period. | 4 weeks |
| Urticaria Control Test | Changes in urticaria control over a 4 week period. | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Asthma Quality of Life Questionnaire | Changes in asthma quality of life over a 4 week period. | 4 weeks |
| Urticaria Activity Score Questionnaire | Changes in the activity of urticaria over a 4 week period. |
| Measure | Description | Time Frame |
|---|---|---|
| Immune biomarkers | Changes in Regulatory T (Treg), Type 1 Regulatory (Tr1), T helper (TH3), T helper 1 (TH1), T helper 2 (TH2), cells, Interferon gamma (IFNg), Interleukin 4 (IL4) and Interleukin 10 (IL10) cytokine production from baseline to 4 weeks. | 4 weeks |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gailen D Marshall, Jr., MD, PhD | University of Mississippi Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Mississippi Medical Center - Allergy, Immunology and Asthma Care Clinic | Jackson | Mississippi | 39216 | United States |
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| ID | Term |
|---|---|
| D003863 | Depression |
| D001249 | Asthma |
| D014581 | Urticaria |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
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|
| 4 weeks |
| Psychological Measures (Composite) | Effects of brief behavioral activation intervention based upon psychological differences including depression and anxiety measured over a 4 week period. | 4 weeks |
| D008173 |
| Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012130 | Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D017445 | Skin Diseases, Vascular |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |