Uveal Melanoma is a rare cancer with approximately 3,000 cases diagnosed in the US every year. Nearly half of these experience spread of their cancer outside the eye. The DecisionDx-UM gene expression test classifies an individual's tumor as low risk (class 1) or high risk (class 2) of spreading. This study is being done to collect information about how physicians are using the DecisionDx-UM results to design individual treatment plans. It will also track outcomes or the uveal melanoma population that received DecisionDx-UM testing.

Inclusion Criteria:

• Patients with a diagnosis of Uveal Melanoma
• Patients whose physician deems them appropriate for DecisionDx-UM testing
• Patients reasonably able to follow up with enrolling physician at regular intervals for assessment of outcome data

Exclusion Criteria:

• Patients with any other form of cancer

Patients diagnosed with uveal melanoma and determined by their treating physician to be appropriate for DecisionDx-UM testing.